Literature DB >> 15724200

Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA.

Anca Dragulescu-Andrasi1, Peng Zhou, Gaofei He, Danith H Ly.   

Abstract

Guanidine-based peptide nucleic acid (GPNA) with a d-backbone configuration and alternate spacing binds sequence-specifically to RNA and is readily taken up by both human somatic and embryonic stem (ES) cells.

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Year:  2004        PMID： 15724200     DOI： 10.1039/b412522c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  17 in total

1.  Recognition of double-stranded RNA by guanidine-modified peptide nucleic acids.

Authors:  Pankaj Gupta; Oluwatoyosi Muse; Eriks Rozners
Journal:  Biochemistry       Date:  2011-12-20       Impact factor: 3.162

2.  Effect of chirality in gamma-PNA: PNA interaction, another piece in the picture.

Authors:  Alex Manicardi; Roberto Corradini
Journal:  Artif DNA PNA XNA       Date:  2014-12-15

Review 3.  The design of guanidinium-rich transporters and their internalization mechanisms.

Authors:  Paul A Wender; Wesley C Galliher; Elena A Goun; Lisa R Jones; Thomas H Pillow
Journal:  Adv Drug Deliv Rev       Date:  2007-11-09       Impact factor: 15.470

4.  Improvement of sequence selectivity in triple helical recognition of RNA by phenylalanine-derived PNA.

Authors:  Thomas Zengeya; Artem Gindin; Eriks Rozners
Journal:  Artif DNA PNA XNA       Date:  2013-10-08

5.  β-Catenin knockdown in liver tumor cells by a cell permeable gamma guanidine-based peptide nucleic acid.

Authors:  Evan Delgado; Raman Bahal; Jing Yang; Jung M Lee; Danith H Ly; Satdarshan P S Monga
Journal:  Curr Cancer Drug Targets       Date:  2013-10       Impact factor: 3.428

6.  Loop and backbone modifications of peptide nucleic acid improve g-quadruplex binding selectivity.

Authors:  Sabrina Lusvarghi; Connor T Murphy; Subhadeep Roy; Farial A Tanious; Iulia Sacui; W David Wilson; Danith H Ly; Bruce A Armitage
Journal:  J Am Chem Soc       Date:  2009-12-30       Impact factor: 15.419

7.  Antitumor effects of EGFR antisense guanidine-based peptide nucleic acids in cancer models.

Authors:  Sufi M Thomas; Bichismita Sahu; Srinivas Rapireddy; Raman Bahal; Sarah E Wheeler; Eva M Procopio; Joseph Kim; Sonali C Joyce; Sarah Contrucci; Yun Wang; Simion I Chiosea; Kira L Lathrop; Simon Watkins; Jennifer R Grandis; Bruce A Armitage; Danith H Ly
Journal:  ACS Chem Biol       Date:  2012-11-09       Impact factor: 5.100

8.  Synthesis of conformationally preorganized and cell-permeable guanidine-based gamma-peptide nucleic acids (gammaGPNAs).

Authors:  Bichismita Sahu; Venugopal Chenna; Kira L Lathrop; Sufi M Thomas; Gerald Zon; Kenneth J Livak; Danith H Ly
Journal:  J Org Chem       Date:  2009-02-20       Impact factor: 4.354

9.  Recent advances in chemical modification of Peptide nucleic acids.

Authors:  Eriks Rozners
Journal:  J Nucleic Acids       Date:  2012-09-06

10.  Cellular uptakes, biostabilities and anti-miR-210 activities of chiral arginine-PNAs in leukaemic K562 cells.

Authors:  Alex Manicardi; Enrica Fabbri; Tullia Tedeschi; Stefano Sforza; Nicoletta Bianchi; Eleonora Brognara; Roberto Gambari; Rosangela Marchelli; Roberto Corradini
Journal:  Chembiochem       Date:  2012-05-25       Impact factor: 3.164
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