| Literature DB >> 15721746 |
Abstract
Dendritic spines, which are present at the vast majority of excitatory synapses in the central nervous system, have a specialized cytoskeleton of dynamic actin filaments that makes them capable of rapid morphological plasticity. During development, structural remodeling of nascent spines is an important factor in experience-dependent shaping of neuronal circuits, whereas in the adult brain spines maintain a balance between morphological stability and plasticity.Entities:
Mesh：
Year: 2005 PMID： 15721746 DOI： 10.1016/j.conb.2005.01.015
Source DB: PubMed Journal: Curr Opin Neurobiol ISSN： 0959-4388 Impact factor: 6.627