Literature DB >> 15719101

Mycobacterium tuberculosis H37Rv3377c encodes the diterpene cyclase for producing the halimane skeleton.

Chiaki Nakano1, Tomoo Okamura, Tsutomu Sato, Tohru Dairi, Tsutomu Hoshino.   

Abstract

The cloning and functional expression of Mycobacterium tuberculosis Rv3377c in Escherichia coli revealed that this gene encodes the diterpene cyclase for producing (+)-5(6),13-halimadiene-15-ol, which accepts geranylgeranyldiphosphate as the intrinsic substrate.

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Year:  2005        PMID： 15719101     DOI： 10.1039/b415346d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  34 in total

1.  Stereoselective Synthesis of 1-Tuberculosinyl Adenosine; a Virulence Factor of Mycobacterium tuberculosis.

Authors:  Jeffrey Buter; Dorus Heijnen; Ieng Chim Wan; F Matthias Bickelhaupt; David C Young; Edwin Otten; D Branch Moody; Adriaan J Minnaard
Journal:  J Org Chem       Date:  2016-07-26       Impact factor: 4.354

Review 2.  Two rings in them all: the labdane-related diterpenoids.

Authors:  Reuben J Peters
Journal:  Nat Prod Rep       Date:  2010-10-01       Impact factor: 13.423

3.  A novel labda-7,13e-dien-15-ol-producing bifunctional diterpene synthase from Selaginella moellendorffii.

Authors:  Sibongile Mafu; Matthew L Hillwig; Reuben J Peters
Journal:  Chembiochem       Date:  2011-07-12       Impact factor: 3.164

4.  Discovery of the Tiancilactone Antibiotics by Genome Mining of Atypical Bacterial Type II Diterpene Synthases.

Authors:  Liao-Bin Dong; Jeffrey D Rudolf; Ming-Rong Deng; Xiaohui Yan; Ben Shen
Journal:  Chembiochem       Date:  2018-05-27       Impact factor: 3.164

5.  Diterpene production in Mycobacterium tuberculosis.

Authors:  Lisa Prach; James Kirby; Jay D Keasling; Tom Alber
Journal:  FEBS J       Date:  2010-07-31       Impact factor: 5.542

Review 6.  Bacterial diterpene synthases: new opportunities for mechanistic enzymology and engineered biosynthesis.

Authors:  Michael J Smanski; Ryan M Peterson; Sheng-Xiong Huang; Ben Shen
Journal:  Curr Opin Chem Biol       Date:  2012-03-22       Impact factor: 8.822

7.  In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection.

Authors:  David C Young; Emilie Layre; Shih-Jung Pan; Asa Tapley; John Adamson; Chetan Seshadri; Zhongtao Wu; Jeffrey Buter; Adriaan J Minnaard; Mireia Coscolla; Sebastien Gagneux; Richard Copin; Joel D Ernst; William R Bishai; Barry B Snider; D Branch Moody
Journal:  Chem Biol       Date:  2015-04-23

8.  Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids.

Authors:  Mamadou Daffé; Dean C Crick; Mary Jackson
Journal:  Microbiol Spectr       Date:  2014

9.  Edaxadiene: a new bioactive diterpene from Mycobacterium tuberculosis.

Authors:  Francis M Mann; Meimei Xu; Xiaoming Chen; D Bruce Fulton; David G Russell; Reuben J Peters
Journal:  J Am Chem Soc       Date:  2009-12-09       Impact factor: 15.419

10.  Characterization and inhibition of a class II diterpene cyclase from Mycobacterium tuberculosis: implications for tuberculosis.

Authors:  Francis M Mann; Sladjana Prisic; Huayou Hu; Meimei Xu; Robert M Coates; Reuben J Peters
Journal:  J Biol Chem       Date:  2009-07-02       Impact factor: 5.157
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