Literature DB >> 15717276

Long-term shedding of infectious epstein-barr virus after infectious mononucleosis.

Samira Fafi-Kremer1, Patrice Morand, Jean-Paul Brion, Patricia Pavese, Monique Baccard, Raphaele Germi, Odile Genoulaz, Sandrine Nicod, Michel Jolivet, Rob W H Ruigrok, Jean-Paul Stahl, Jean-Marie Seigneurin.   

Abstract

Epstein-Barr virus (EBV) DNA loads in peripheral blood mononuclear cells (PBMCs), plasma, and saliva, as well as infectivity of the virus in saliva, were evaluated in 20 patients for 6 months after the onset of infectious mononucleosis (IM). All patients displayed sustained high EBV DNA loads in the saliva, associated with a persistent infectivity of saliva at day 180. EBV DNA load in PBMCs decreased significantly from day 0 to day 180 (in spite of a viral rebound between day 30 and day 90 in 90% of the patients), and EBV DNA rapidly disappeared from plasma. These data show that patients with IM remain highly infectious during convalescence.

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Year:  2005        PMID： 15717276     DOI： 10.1086/428097

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  30 in total

1.  Validation of Roche LightCycler Epstein-Barr virus quantification reagents in a clinical laboratory setting.

Authors:  Margaret L Gulley; Hongxin Fan; Sandra H Elmore
Journal:  J Mol Diagn       Date:  2006-11       Impact factor: 5.568

2.  On the dynamics of acute EBV infection and the pathogenesis of infectious mononucleosis.

Authors:  Vey Hadinoto; Michael Shapiro; Thomas C Greenough; John L Sullivan; Katherine Luzuriaga; David A Thorley-Lawson
Journal:  Blood       Date:  2007-11-08       Impact factor: 22.113

3.  Evaluation of the Epstein-Barr virus R-gene quantification kit in whole blood with different extraction methods and PCR platforms.

Authors:  Samira Fafi-Kremer; Patrice Morand; Come Barranger; Gérard Barguès; Stéphane Magro; Jérôme Bés; Philippe Bourgeois; Martine Joannes; Jean-Marie Seigneurin
Journal:  J Mol Diagn       Date:  2007-12-28       Impact factor: 5.568

Review 4.  Serological diagnosis of Epstein-Barr virus infection: Problems and solutions.

Authors:  Massimo De Paschale; Pierangelo Clerici
Journal:  World J Virol       Date:  2012-02-12

Review 5.  Epstein-Barr virus in the pathogenesis of oral cancers.

Authors:  J T Guidry; C E Birdwell; R S Scott
Journal:  Oral Dis       Date:  2017-04-18       Impact factor: 3.511

6.  Epstein-Barr virus infection of Langerhans cell precursors as a mechanism of oral epithelial entry, persistence, and reactivation.

Authors:  Dennis M Walling; Autumn J Ray; Joan E Nichols; Catherine M Flaitz; C Mark Nichols
Journal:  J Virol       Date:  2007-03-21       Impact factor: 5.103

Review 7.  Progress and problems in understanding and managing primary Epstein-Barr virus infections.

Authors:  Oludare A Odumade; Kristin A Hogquist; Henry H Balfour
Journal:  Clin Microbiol Rev       Date:  2011-01       Impact factor: 26.132

8.  Stress-related Epstein-Barr virus reactivation.

Authors:  Omer Coskun; Kenan Sener; Selim Kilic; Hakan Erdem; Halil Yaman; Ahmet Bulent Besirbellioglu; Hanefi Cem Gul; Can Polat Eyigun
Journal:  Clin Exp Med       Date:  2009-09-25       Impact factor: 3.984

9.  The dynamics of EBV shedding implicate a central role for epithelial cells in amplifying viral output.

Authors:  Vey Hadinoto; Michael Shapiro; Chia Chi Sun; David A Thorley-Lawson
Journal:  PLoS Pathog       Date:  2009-07-03       Impact factor: 6.823

10.  Priming of protective T cell responses against virus-induced tumors in mice with human immune system components.

Authors:  Till Strowig; Cagan Gurer; Alexander Ploss; Yi-Fang Liu; Frida Arrey; Junji Sashihara; Gloria Koo; Charles M Rice; James W Young; Amy Chadburn; Jeffrey I Cohen; Christian Münz
Journal:  J Exp Med       Date:  2009-06-01       Impact factor: 14.307
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