Literature DB >> 15715939

Transforming growth factor-beta : biology and clinical relevance.

Isaac Yi Kim1, Moses M Kim, Seong-Jin Kim.   

Abstract

Transforming growth factor-beta is a pleiotropic growth factor that has enthralled many investigators for approximately two decades. In addition to many reports that have clarified the basic mechanism of transforming growth factor-beta signal transduction, numerous laboratories have published on the clinical implication/application of transforming growth factor-beta . To name a few, dysregulation of transforming growth factor-beta signaling plays a role in carcinogenesis, autoimmunity, angiogenesis, and wound healing. In this report, we will review these clinical implications of transforming growth factor-beta .

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Year:  2005        PMID: 15715939     DOI: 10.5483/bmbrep.2005.38.1.001

Source DB:  PubMed          Journal:  J Biochem Mol Biol        ISSN: 1225-8687


  23 in total

1.  Esophageal anastomosis - how the granulation phase of wound healing improves the incidence of anastomotic leakage.

Authors:  Renata Tabola; Katarzyna Augoff; Andrzej Lewandowski; Piotr Ziolkowski; Piotr Szelachowski; Krzysztof Grabowski
Journal:  Oncol Lett       Date:  2016-07-18       Impact factor: 2.967

2.  Transforming growth factor-β signaling pathway activation in Keratoconus.

Authors:  Christoph Engler; Shukti Chakravarti; Jefferson Doyle; Charles G Eberhart; Huan Meng; Walter J Stark; Clare Kelliher; Albert S Jun
Journal:  Am J Ophthalmol       Date:  2011-02-18       Impact factor: 5.258

3.  Transforming growth factor-β1 and tumor necrosis factor-α are associated with clinical severity and airflow limitation of COPD in an additive manner.

Authors:  Chi-Huei Chiang; Chiao-Hui Chuang; Shiou-Ling Liu
Journal:  Lung       Date:  2013-10-24       Impact factor: 2.584

4.  The functional class evaluated in rheumatoid arthritis is associated with soluble TGF-β1 serum levels but not with G915C (Arg25Pro) TGF-β1 polymorphism.

Authors:  José Francisco Muñoz-Valle; Nora Magdalena Torres-Carrillo; Iris Paola Guzmán-Guzmán; Norma Torres-Carrillo; Sandra Luz Ruiz-Quezada; Claudia Azucena Palafox-Sánchez; Héctor Rangel-Villalobos; María Guadalupe Ramírez-Dueñas; Isela Parra-Rojas; Mary Fafutis-Morris; Blanca Estela Bastidas-Ramírez; Ana Laura Pereira-Suárez
Journal:  Rheumatol Int       Date:  2010-11-27       Impact factor: 2.631

5.  Transforming growth factor beta and soluble endoglin in the healthy senior and in Alzheimer's disease patients.

Authors:  B Juraskova; C Andrys; I Holmerova; D Solichova; D Hrnciarikova; H Vankova; T Vasatko; J Krejsek
Journal:  J Nutr Health Aging       Date:  2010-11       Impact factor: 4.075

6.  Radiotherapy suppresses angiogenesis in mice through TGF-betaRI/ALK5-dependent inhibition of endothelial cell sprouting.

Authors:  Natsuko Imaizumi; Yan Monnier; Monika Hegi; René-Olivier Mirimanoff; Curzio Rüegg
Journal:  PLoS One       Date:  2010-06-11       Impact factor: 3.240

7.  Expression, purification and characterization of BG(E)RII: a novel pan-TGFbeta inhibitor.

Authors:  Erik V Verona; Yuping Tang; Thomas K Millstead; Andrew P Hinck; Joseph K Agyin; Lu-Zhe Sun
Journal:  Protein Eng Des Sel       Date:  2008-05-21       Impact factor: 1.650

8.  Investigation of TGFB2 as a candidate gene in multiple sclerosis and Parkinson's disease.

Authors:  A Goris; C H Williams-Gray; T Foltynie; J Brown; M Maranian; A Walton; D A S Compston; R A Barker; S J Sawcer
Journal:  J Neurol       Date:  2007-07       Impact factor: 4.849

9.  Contribution of the TGFB1 Gene 
to Myocardial Infarction Susceptibility.

Authors:  R M Barsova; B V Titov; N A Matveeva; A V Favorov; T S Sukhinina; R M Shahnovich; M Ia Ruda; O O Favorova
Journal:  Acta Naturae       Date:  2012-04       Impact factor: 1.845

Review 10.  Critical Role of Transforming Growth Factor Beta in Different Phases of Wound Healing.

Authors:  Mohammadreza Pakyari; Ali Farrokhi; Mohsen Khosravi Maharlooei; Aziz Ghahary
Journal:  Adv Wound Care (New Rochelle)       Date:  2013-06       Impact factor: 4.730

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