Literature DB >> 15706437

Role of proteases in pancreatic carcinoma.

Lane C Patten1, David H Berger.   

Abstract

Proteases play an important role in cancer invasion and metastasis. In this review we specifically discuss the role of these proteases in pancreatic carcinoma. Serine proteases and matrix metalloproteinases are the focus of intense research, as they appear to be related to the process of tumor progression. We discuss the diagnostic and prognostic value of these two groups of proteases. Lastly, we report on the current and recent clinical trials focusing on inhibition of these proteases.

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Year:  2005        PMID： 15706437     DOI： 10.1007/s00268-004-7816-3

Source DB:  PubMed          Journal:  World J Surg        ISSN： 0364-2313            Impact factor:   3.352


  75 in total

1.  Proteolytic activation of the precursor of membrane type 1 matrix metalloproteinase by human plasmin. A possible cell surface activator.

Authors:  Y Okumura; H Sato; M Seiki; H Kido
Journal:  FEBS Lett       Date:  1997-02-03       Impact factor: 4.124

2.  Detection of serum MMPs in tumor-bearing hamsters.

Authors:  Katsumichi Iki; Tomoyuki Takeo; Tadahiko Kubozoe; Shinichi Aoki; Jiro Hayashi; Tsukasa Tsunoda
Journal:  J Hepatobiliary Pancreat Surg       Date:  2002

3.  Tissue plasminogen activator is required for the growth, invasion, and angiogenesis of pancreatic tumor cells.

Authors:  Víctor M Díaz; Jesús Planaguma; Timothy M Thomson; Jaume Reventós; Rosanna Paciucci
Journal:  Gastroenterology       Date:  2002-03       Impact factor: 22.682

4.  Plasminogen activator profiles in neoplastic tissues of the human colon.

Authors:  P A de Bruin; G Griffioen; H W Verspaget; J H Verheijen; G Dooijewaard; H F van den Ingh; C B Lamers
Journal:  Cancer Res       Date:  1988-08-15       Impact factor: 12.701

5.  Comparison of matrix metalloproteinase expression between primary tumors with or without liver metastasis in pancreatic and colorectal carcinomas.

Authors:  Yoshito Matsuyama; Sonshin Takao; Takashi Aikou
Journal:  J Surg Oncol       Date:  2002-06       Impact factor: 3.454

6.  Distribution of extracellular matrix proteins in pancreatic ductal adenocarcinoma and its influence on tumor cell proliferation in vitro.

Authors:  J Mollenhauer; I Roether; H F Kern
Journal:  Pancreas       Date:  1987       Impact factor: 3.327

7.  Immunohistochemical study of heparan sulfate proteoglycan in adenocarcinomas of the pancreas.

Authors:  Z H Wang; T Manabe; G Ohshio; T Imamura; T Yoshimura; H Suwa; S Ishigami; T Kyogoku
Journal:  Pancreas       Date:  1994-11       Impact factor: 3.327

8.  Active immunogene therapy of cancer with vaccine on the basis of chicken homologous matrix metalloproteinase-2.

Authors:  Jing-Mei Su; Yu-Quan Wei; Ling Tian; Xia Zhao; Li Yang; Qiu-Ming He; Yu Wang; You Lu; Yang Wu; Fen Liu; Ji-Yan Liu; Jin-Liang Yang; Yan-Yan Lou; Bing Hu; Ting Niu; Yan-Jun Wen; Fei Xiao; Hong-Xin Deng; Jiong Li; Bing Kan
Journal:  Cancer Res       Date:  2003-02-01       Impact factor: 12.701

Review 9.  Epidemiologic and etiologic factors of pancreatic cancer.

Authors:  Albert B Lowenfels; Patrick Maisonneuve
Journal:  Hematol Oncol Clin North Am       Date:  2002-02       Impact factor: 3.722

10.  A phase II trial of marimastat in advanced pancreatic cancer.

Authors:  J D Evans; A Stark; C D Johnson; F Daniel; J Carmichael; J Buckels; C W Imrie; P Brown; J P Neoptolemos
Journal:  Br J Cancer       Date:  2001-12-14       Impact factor: 7.640
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  3 in total

Review 1.  Application of activity-based probes to the study of enzymes involved in cancer progression.

Authors:  Margot G Paulick; Matthew Bogyo
Journal:  Curr Opin Genet Dev       Date:  2008-02-21       Impact factor: 5.578

2.  Comparative evaluation of serum alpha-1antitrypsin levels in patients with oral squamous cell carcinoma and in subjects with tobacco habit without carcinoma.

Authors:  Upasana S Ahuja; Nidhi Puri; Anjana Bagewadi; Vaishali Keluskar; Anshuman Ahuja; Harkanwal P Singh
Journal:  J Family Med Prim Care       Date:  2019-11-15

3.  Kallikrein-related peptidase 7 is a potential target for the treatment of pancreatic cancer.

Authors:  Jian Ping Du; Lin Li; Jun Zheng; Ding Zhang; Wei Liu; Wei Hong Zheng; Xiao Song Li; Ru Cheng Yao; Fangyu Wang; Sen Liu; Xiao Tan
Journal:  Oncotarget       Date:  2018-01-10
  3 in total

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