Literature DB >> 15702642

Anti-inflammatory furanogermacrane sesquiterpenes from Neolitsea parvigemma.

Keh-Shaw Chen1, Pei-Wen Hsieh, Tsong-Long Hwang, Fang-Rong Chang, Yang-Chang Wu.   

Abstract

Six furanogermacrane sesquiterpenes, pseudoneolinderane (1), linderalactone (2), zeylanidine (3), zeylanicine (4), deacetylzeylanidine (5), and neolitrane (6), isolated from the stems of Neolitsea parvigemma, were tested for anti-inflammatory activities. Among them, 1 and 2 showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB. The IC50 of 1 and 2 were found to be 3.21 and 8.48 microg/mL, respectively.

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Year:  2005        PMID： 15702642     DOI： 10.1080/14786410410001714669

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  6 in total

Review 1.  Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives.

Authors:  Igor A Schepetkin; Andrei I Khlebnikov; Liliya N Kirpotina; Mark T Quinn
Journal:  Int Immunopharmacol       Date:  2015-09-15       Impact factor: 4.932

2.  Immunomodulatory Effects of Taiwanese Neolitsea Species on Th1 and Th2 Functionality.

Authors:  Yin-Hua Cheng; Ying-Chi Lin; Ih-Sheng Chen; Sian-De Liu; Jih-Heng Li; Chia-Chi Wang
Journal:  J Immunol Res       Date:  2017-07-11       Impact factor: 4.818

3.  Attenuation of antigen-specific T helper 1 immunity by Neolitsea hiiranensis and its derived terpenoids.

Authors:  Yin-Hua Cheng; Ih-Sheng Chen; Ying-Chi Lin; Chun-Wei Tung; Hsun-Shuo Chang; Chia-Chi Wang
Journal:  PeerJ       Date:  2016-12-07       Impact factor: 2.984

4.  Linderalactone Suppresses Pancreatic Cancer Development In Vitro and In Vivo via Negatively Regulating PI3K/AKT Signaling Pathway.

Authors:  Dongchao Xu; Mengyao Tian; Wangyang Chen; Ying Bian; Xiaofeng Xia; Qiang Liu; Liyun Zheng; Xiaofeng Zhang; Hongzhang Shen
Journal:  J Oncol       Date:  2022-08-04       Impact factor: 4.501

5.  Chemical Constituent of β-Glucuronidase Inhibitors from the Root of Neolitsea acuminatissima.

Authors:  Chu-Hung Lin; Hsiao-Jung Chou; Chih-Chi Chang; Ih-Sheng Chen; Hsun-Shuo Chang; Tian-Lu Cheng; Yueh-Hsiung Kuo; Horng-Huey Ko
Journal:  Molecules       Date:  2020-11-06       Impact factor: 4.411

Review 6.  Chemical constituents and bioactivity of Formosan lauraceous plants.

Authors:  Hsun-Shuo Chang; Ih-Sheng Chen
Journal:  J Food Drug Anal       Date:  2016-01-05       Impact factor: 6.157
  6 in total

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