Literature DB >> 15700070

Reversible Michael addition of thiols as a new tool for dynamic combinatorial chemistry.

Baolu Shi1, Michael F Greaney.   

Abstract

The Michael addition of thiols to enones is reported as a new method for dynamic combinatorial library synthesis.

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Year:  2005        PMID： 15700070     DOI： 10.1039/b414300k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  21 in total

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3.  In-situ generation of differential sensors that fingerprint kinases and the cellular response to their expression.

Authors:  Diana Zamora-Olivares; Tamer S Kaoud; Kevin N Dalby; Eric V Anslyn
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4.  Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry.

Authors:  Venugopal T Bhat; Anne M Caniard; Torsten Luksch; Ruth Brenk; Dominic J Campopiano; Michael F Greaney
Journal:  Nat Chem       Date:  2010-05-16       Impact factor: 24.427

5.  17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor-α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure-Activity Relationships.

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Review 6.  Click Chemistry and Radiochemistry: The First 10 Years.

Authors:  Jan-Philip Meyer; Pierre Adumeau; Jason S Lewis; Brian M Zeglis
Journal:  Bioconjug Chem       Date:  2016-11-22       Impact factor: 4.774

7.  Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring.

Authors:  A E Kuriyan; G M Lehmann; A A Kulkarni; C F Woeller; S E Feldon; H B Hindman; P J Sime; K R Huxlin; R P Phipps
Journal:  Exp Eye Res       Date:  2011-12-08       Impact factor: 3.467

8.  Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.

Authors:  Heather E Ferguson; Ajit Kulkarni; Geniece M Lehmann; Tatiana M Garcia-Bates; Thomas H Thatcher; Krystel R Huxlin; Richard P Phipps; Patricia J Sime
Journal:  Am J Respir Cell Mol Biol       Date:  2009-03-13       Impact factor: 6.914

9.  Moving known libraries to an addressable array: a site-selective hetero-Michael reaction.

Authors:  Melissae Stuart; Karl Maurer; Kevin D Moeller
Journal:  Bioconjug Chem       Date:  2008-07-25       Impact factor: 4.774

10.  Michael acceptor approach to the design of new salvinorin A-based high affinity ligands for the kappa-opioid receptor.

Authors:  Prabhakar R Polepally; Krzysztof Huben; Eyal Vardy; Vincent Setola; Philip D Mosier; Bryan L Roth; Jordan K Zjawiony
Journal:  Eur J Med Chem       Date:  2014-08-23       Impact factor: 6.514
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