Literature DB >> 15699436

Relationship between intracranial granulomas and cerebrospinal fluid levels of gamma interferon and interleukin-10 in patients with tuberculous meningitis.

Adel M Mansour1, Robert W Frenck, Toni Darville, Isabelle A Nakhla, Thomas F Wierzba, Yehia Sultan, Magdy I Bassiouny, Kathryn McCarthy, Richard F Jacobs.   

Abstract

Cerebrospinal fluid gamma interferon (IFN-gamma) and interleukin-10 levels in 39 patients with tuberculous meningitis were serially measured. Cytokine levels did not predict intracranial granuloma (IG) development, but IFN-gamma levels in the top quartile after 1 month of therapy were highly associated (odds ratio = 18) with detection of an IG by computed tomography scanning.

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Year:  2005        PMID： 15699436      PMCID： PMC549309          DOI： 10.1128/CDLI.12.2.363-365.2005

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  13 in total

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Review 2.  The role of IL-10 in crossregulation of TH1 and TH2 responses.

Authors:  T R Mosmann; K W Moore
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Journal:  Rev Infect Dis       Date:  1991 Nov-Dec

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  3 in total

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