Literature DB >> 1648926

The role of IL-10 in crossregulation of TH1 and TH2 responses.

T R Mosmann1, K W Moore.   

Abstract

The identification of helper T (TH)-cell subsets has greatly improved understanding of the regulation of immune effector functions. In addition to controlling humoral and delayed-type hypersensitivity responses, these subsets crossregulate by secreting mutually inhibitory cytokines. In this review, Tim Mosmann and Kevin Moore examine these phenomena and in particular the role of interleukin 10, a cytokine secreted by TH2 cells that inhibits TH1-cell function.

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Year:  1991        PMID： 1648926     DOI： 10.1016/S0167-5699(05)80015-5

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  154 in total

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Review 4.  Langerhans cells are initiators of the immunosuppressive effect of ultraviolet B radiation.

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Review 5.  Induction of T helper cell subsets.

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7.  Anti-Asthmatic Effects of Ginsenoside Rb1 in a Mouse Model of Allergic Asthma Through Relegating Th1/Th2.

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8.  Cytokine expression in squamous intraepithelial lesions of the uterine cervix: implications for the generation of local immunosuppression.

Authors:  S L Giannini; W Al-Saleh; H Piron; N Jacobs; J Doyen; J Boniver; P Delvenne
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9.  B cells are required for the switch from Th1- to Th2-regulated immune responses to Plasmodium chabaudi chabaudi infection.

Authors:  A W Taylor-Robinson; R S Phillips
Journal:  Infect Immun       Date:  1994-06       Impact factor: 3.441

10.  Profiles of immunoregulatory cytokine production in vitro in patients with IgA nephropathy and their kindred.

Authors:  V Scivittaro; L Gesualdo; E Ranieri; C Marfella; S A Schewn; S N Emancipator; F P Schena
Journal:  Clin Exp Immunol       Date:  1994-05       Impact factor: 4.330
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