| Literature DB >> 15699435 |
Lidice Bernardo1, Adriana Yndart, Susana Vázquez, Luis Morier, María G Guzmán.
Abstract
The possibility of a correlation between dengue virus genotype groups and disease severity is currently under discussion. The objective of this investigation was to identify any immunogenic difference between the American and Asian dengue 2 virus genotypes through the study of antibody development (virus-binding immunoglobulin G and neutralizing antibodies) in mice. Differences in the neutralization pattern between the strains studied were observed, suggesting the presence of slight antigenic variations among them. The lack of recognition of one of the Asian genotype strains was remarkable.Entities:
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Year: 2005 PMID: 15699435 PMCID: PMC549307 DOI: 10.1128/CDLI.12.2.361-362.2005
Source DB: PubMed Journal: Clin Diagn Lab Immunol ISSN: 1071-412X