INTRODUCTION: Overwhelming post-splenectomy infection (OPSI) has a 50-70% mortality rate and carries a lifetime risk for the asplenic patient. Specific British guidelines have been developed to reduce its incidence. AIMS: To determine whether British guidelines were being followed in our own institution and what impact they had on overwhelming post-splenectomy infection. METHODS: Retrospective chart review of 100 splenectomies performed by Department of Surgery, Beaumont Hospital from January 1990 to January 2000. RESULTS: Twenty per cent of patients were discharged without any recommended vaccinations. Prophylactic antibiotics were not prescribed in 53% of patients. Just 12% of charts document a verbal explanation of the complications and management of asplenia to the patient. Overall septic mortality was 12%, of whom 8% died in hospital and 4% after discharge. CONCLUSION: Management of the asplenic patient has improved but is far from complete. A central register of asplenic patients and national asplenic guidelines should be established in Ireland to ensure optimum patient care.
INTRODUCTION: Overwhelming post-splenectomy infection (OPSI) has a 50-70% mortality rate and carries a lifetime risk for the asplenic patient. Specific British guidelines have been developed to reduce its incidence. AIMS: To determine whether British guidelines were being followed in our own institution and what impact they had on overwhelming post-splenectomy infection. METHODS: Retrospective chart review of 100 splenectomies performed by Department of Surgery, Beaumont Hospital from January 1990 to January 2000. RESULTS: Twenty per cent of patients were discharged without any recommended vaccinations. Prophylactic antibiotics were not prescribed in 53% of patients. Just 12% of charts document a verbal explanation of the complications and management of asplenia to the patient. Overall septic mortality was 12%, of whom 8% died in hospital and 4% after discharge. CONCLUSION: Management of the asplenic patient has improved but is far from complete. A central register of asplenic patients and national asplenic guidelines should be established in Ireland to ensure optimum patient care.
Authors: A J J Lammers; D Veninga; M J M H Lombarts; J B L Hoekstra; P Speelman Journal: Eur J Clin Microbiol Infect Dis Date: 2010-01-22 Impact factor: 3.267
Authors: Vanessa Meier-Stephenson; Shelly McNeil; Andrea Kew; Jennifer Sweetapple; Kara Thompson; Kathryn Slayter Journal: Can J Hosp Pharm Date: 2014-07