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Literature DB >> 15687022

Mouse and guinea pig models for testing new tuberculosis vaccines.

Abstract

Animal models of pulmonary tuberculosis in the mouse and guinea pig contain to provide new information about the host response in the lungs, changes in immunopathology, and the protective effect of new vaccine candidates. These include Mtb72F, a polyprotein vaccine that gives excellent protection and also boosts and prolongs the protective effect of the BCG vaccine.

Entities: Disease Species

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Year: 2005 PMID： 15687022 DOI： 10.1016/j.tube.2004.08.001

Source DB: PubMed Journal: Tuberculosis (Edinb) ISSN： 1472-9792 Impact factor: 3.131

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Cited

15 in total

1. BCG vaccination in the cotton rat (Sigmodon hispidus) infected by the pulmonary route with virulent Mycobacterium tuberculosis.

Authors: Christine T McFarland; Lan Ly; Amminikutty Jeevan; Toshiko Yamamoto; Bradley Weeks; Angelo Izzo; David McMurray
Journal: Tuberculosis (Edinb) Date: 2010-05-06 Impact factor: 3.131

2. Development of an anti-guinea pig CD4 monoclonal antibody for depletion of CD4+ T cells in vivo.

Authors: Brianne N Banasik; Clarice L Perry; Celeste A Keith; Nigel Bourne; Hubert Schäfer; Gregg N Milligan
Journal: J Immunol Methods Date: 2019-08-14 Impact factor: 2.303

3. Mice continue to be a good model for preliminary assessment of tuberculosis vaccine candidates.

Authors: Michel de Jesús Aceves-Sánchez; Mario Alberto Flores-Valdez
Journal: Hum Vaccin Immunother Date: 2016-10-20 Impact factor: 3.452

4. HspX vaccination and role in virulence in the guinea pig model of tuberculosis.

Authors: Agatha E Wieczorek; Jolynn L Troudt; Phillip Knabenbauer; Jennifer Taylor; Rebecca L Pavlicek; Russell Karls; Anne Hess; Rebecca M Davidson; Michael Strong; Helle Bielefeldt-Ohmann; Angelo A Izzo; Karen M Dobos
Journal: Pathog Dis Date: 2014-02-24 Impact factor: 3.166

Mouse and guinea pig models for testing new tuberculosis vaccines.

1. BCG vaccination in the cotton rat (Sigmodon hispidus) infected by the pulmonary route with virulent Mycobacterium tuberculosis.

2. Development of an anti-guinea pig CD4 monoclonal antibody for depletion of CD4+ T cells in vivo.

3. Mice continue to be a good model for preliminary assessment of tuberculosis vaccine candidates.

4. HspX vaccination and role in virulence in the guinea pig model of tuberculosis.

5. Granuloma encapsulation is a key factor for containing tuberculosis infection in minipigs.

6. Animal models of mycobacteria infection.

Review 7. The guinea pig as a model of infectious diseases.

Review 8. Current and novel approaches to vaccine development against tuberculosis.

9. Modeling the Mycobacterium tuberculosis Granuloma - the Critical Battlefield in Host Immunity and Disease.

10. Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis.