Literature DB >> 15679374

Platination of nucleobases to enhance noncovalent recognition in protein-DNA/RNA complexes.

Atilio I Anzellotti1, Erin S Ma, Nicholas Farrell.   

Abstract

Fluorescence quenching experiments show that the stacking interaction between nucleic acid bases and l-tryptophan is enhanced significantly upon base coordination to a metal center such as Pt(II), and the biological implications of such enhancement are discussed.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 15679374     DOI： 10.1021/ic049086d

Source DB:  PubMed          Journal:  Inorg Chem        ISSN： 0020-1669            Impact factor:   5.165


  3 in total

1.  Extrinsic interactions dominate helical propensity in coupled binding and folding of the lactose repressor protein hinge helix.

Authors:  Hongli Zhan; Liskin Swint-Kruse; Kathleen Shive Matthews
Journal:  Biochemistry       Date:  2006-05-09       Impact factor: 3.162

2.  Dinuclear platinum complexes containing planar aromatic ligands to enhance stacking interactions with proteins.

Authors:  Erin S F Ma; A Gerard Daniel; Nicholas P Farrell
Journal:  ChemMedChem       Date:  2014-05-06       Impact factor: 3.466

3.  Enhancement of the physicochemical properties of [Pt(dien)(nucleobase)]2+ for HIVNCp7 targeting.

Authors:  S D Tsotsoros; P B Lutz; A G Daniel; E J Peterson; R E F de Paiva; E Rivera; Y Qu; C A Bayse; N P Farrell
Journal:  Chem Sci       Date:  2016-10-06       Impact factor: 9.825
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.