Literature DB >> 15679105

Keratinocyte growth factor: effects on keratinocytes and mechanisms of action.

Ulrich auf demKeller1, Monika Krampert, Angelika Kümin, Susanne Braun, Sabine Werner.   

Abstract

Keratinocyte growth factor (KGF) is a potent and specific mitogen for different types of epithelial cells, and it can protect these cells from various insults. Due to these properties, it is of particular importance for the repair of injured epithelial tissues, and it is currently therapeutically explored for the treatment of radiation- and chemotherapy-induced mucosal epithelial damage in cancer patients. In this review we summarize the current knowledge on the role of KGF in tissue repair and cytoprotection, and we report on its mechanisms of action in keratinocytes.

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Year:  2004        PMID： 15679105     DOI： 10.1078/0171-9335-00389

Source DB:  PubMed          Journal:  Eur J Cell Biol        ISSN： 0171-9335            Impact factor:   4.492


  19 in total

1.  Fibroblast growth factor-7 facilitates osteogenic differentiation of embryonic stem cells through the activation of ERK/Runx2 signaling.

Authors:  Young-Mi Jeon; Sung-Ho Kook; Sang-Jung Rho; Shin-Saeng Lim; Ki-Choon Choi; Hee-Soon Kim; Jong-Ghee Kim; Jeong-Chae Lee
Journal:  Mol Cell Biochem       Date:  2013-06-04       Impact factor: 3.396

2.  The effects of adenoviral transfection of the keratinocyte growth factor gene on epidermal stem cells: an in vitro study.

Authors:  Xinping Li; Ling Liang; Pin Zhao; Kenzo Uchida; Hisatoshi Baba; Hong Huang; Wenfang Bai; Liming Bai; Mingsheng Zhang
Journal:  Mol Cells       Date:  2013-10-22       Impact factor: 5.034

Review 3.  Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 2: role of growth factors in normal and pathological wound healing: therapeutic potential and methods of delivery.

Authors:  Tatiana N Demidova-Rice; Michael R Hamblin; Ira M Herman
Journal:  Adv Skin Wound Care       Date:  2012-08       Impact factor: 2.347

4.  Re-epithelialization of cutaneous wounds in adult zebrafish combines mechanisms of wound closure in embryonic and adult mammals.

Authors:  Rebecca Richardson; Manuel Metzger; Philipp Knyphausen; Thomas Ramezani; Krasimir Slanchev; Christopher Kraus; Elmon Schmelzer; Matthias Hammerschmidt
Journal:  Development       Date:  2016-04-27       Impact factor: 6.868

5.  KGF Promotes Paracrine Activation of the SCF/c-KIT Axis from Human Keratinocytes to Melanoma Cells.

Authors:  Francesca Belleudi; Giorgia Cardinali; Daniela Kovacs; Mauro Picardo; Maria Rosaria Torrisi
Journal:  Transl Oncol       Date:  2010-04       Impact factor: 4.243

6.  The Role of Fgf Signaling on Epithelial Cell Differentiation in Mouse Vagina.

Authors:  Y U Hirano; Kentaro Suzuki; Taisen Iguchi; Gen Yamada; Shinichi Miyagawa
Journal:  In Vivo       Date:  2019 Sep-Oct       Impact factor: 2.155

Review 7.  Hyperphosphatemic familial tumoral calcinosis secondary to fibroblast growth factor 23 (FGF23) mutation: a report of two affected families and review of the literature.

Authors:  M Chakhtoura; M S Ramnitz; N Khoury; G Nemer; N Shabb; A Abchee; A Berberi; M Hourani; M Collins; S Ichikawa; G El Hajj Fuleihan
Journal:  Osteoporos Int       Date:  2018-06-20       Impact factor: 4.507

8.  Keratinocyte Growth Factor (KGF) Modulates Epidermal Progenitor Cell Kinetics through Activation of p63 in Middle Ear Cholesteatoma.

Authors:  Tomomi Yamamoto-Fukuda; Naotaro Akiyama; Masahiro Takahashi; Hiromi Kojima
Journal:  J Assoc Res Otolaryngol       Date:  2018-03-16

9.  Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin.

Authors:  Nichole M Danzl; Laura T Donlin; Konstantina Alexandropoulos
Journal:  J Exp Med       Date:  2010-04-19       Impact factor: 14.307

10.  Familial tumoral calcinosis: from characterization of a rare phenotype to the pathogenesis of ectopic calcification.

Authors:  Eli Sprecher
Journal:  J Invest Dermatol       Date:  2009-10-29       Impact factor: 8.551
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