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Literature DB >> 15676295

High-throughput drug discovery: what can we expect from HTS?

Phillip Gribbon¹, Andreas Sewing.

Abstract

Mesh：

Year: 2005 PMID： 15676295 DOI： 10.1016/S1359-6446(04)03275-1

Source DB: PubMed Journal: Drug Discov Today ISSN： 1359-6446 Impact factor: 7.851

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21 in total

1. Advances in Nuclear Magnetic Resonance for Drug Discovery.

Authors: Robert Powers
Journal: Expert Opin Drug Discov Date: 2009-10-01 Impact factor: 6.098

2. Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease.

Authors: Wei Zheng; Janak Padia; Daniel J Urban; Ajit Jadhav; Ozlem Goker-Alpan; Anton Simeonov; Ehud Goldin; Douglas Auld; Mary E LaMarca; James Inglese; Christopher P Austin; Ellen Sidransky
Journal: Proc Natl Acad Sci U S A Date: 2007-08-01 Impact factor: 11.205

3. Comparative virtual screening and novelty detection for NMDA-GlycineB antagonists.

Authors: Bjoern A Krueger; Tanja Weil; Gisbert Schneider
Journal: J Comput Aided Mol Des Date: 2009-11-05 Impact factor: 3.686

4. Targeting metalloproteins by fragment-based lead discovery.

Authors: Sherida Johnson; Elisa Barile; Biancamaria Farina; Angela Purves; Jun Wei; Li-Hsing Chen; Sergey Shiryaev; Ziming Zhang; Irina Rodionova; Arpita Agrawal; Seth M Cohen; Andrei Osterman; Alex Strongin; Maurizio Pellecchia
Journal: Chem Biol Drug Des Date: 2011-06-16 Impact factor: 2.817

5. Rapid and quantitative measurement of metabolic stability without chromatography or mass spectrometry.

Authors: Matthew J Traylor; Jessica D Ryan; Eric S Arnon; Jonathan S Dordick; Douglas S Clark
Journal: J Am Chem Soc Date: 2011-07-27 Impact factor: 15.419

Review 6. Structure-based drug screening for G-protein-coupled receptors.

Authors: Brian K Shoichet; Brian K Kobilka
Journal: Trends Pharmacol Sci Date: 2012-04-13 Impact factor: 14.819

7. Conjugation of Hot-Melt Extrusion with High-Pressure Homogenization: a Novel Method of Continuously Preparing Nanocrystal Solid Dispersions.

Authors: Xingyou Ye; Hemlata Patil; Xin Feng; Roshan V Tiwari; Jiannan Lu; Andreas Gryczke; Karl Kolter; Nigel Langley; Soumyajit Majumdar; Dipesh Neupane; Sanjay R Mishra; Michael A Repka
Journal: AAPS PharmSciTech Date: 2015-08-18 Impact factor: 3.246