Literature DB >> 15675723

New developments in diagnosis and treatment of Parkinson's disease--from basic science to clinical applications.

Alexander Storch1, Anne Hofer, Rejko Krüger, Jörg B Schulz, Jürgen Winkler, Manfred Gerlach.   

Abstract

In this review we summarize new developments in early diagnosis, establishing surrogate markers, genetics, neuroprotection and cell replacement in Parkinson's disease. Furthermore, we discuss the major problems in the translation of results from preclinical research into successful clinical trials.

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Year:  2004        PMID： 15675723     DOI： 10.1007/s00415-004-1608-4

Source DB:  PubMed          Journal:  J Neurol        ISSN： 0340-5354            Impact factor:   4.849


  30 in total

1.  Association between early-onset Parkinson's disease and mutations in the parkin gene.

Authors:  C B Lücking; A Dürr; V Bonifati; J Vaughan; G De Michele; T Gasser; B S Harhangi; G Meco; P Denèfle; N W Wood; Y Agid; A Brice
Journal:  N Engl J Med       Date:  2000-05-25       Impact factor: 91.245

2.  Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.

Authors:  S H Lee; N Lumelsky; L Studer; J M Auerbach; R D McKay
Journal:  Nat Biotechnol       Date:  2000-06       Impact factor: 54.908

3.  Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.

Authors:  A Hartmann; S Hunot; P P Michel; M P Muriel; S Vyas; B A Faucheux; A Mouatt-Prigent; H Turmel; A Srinivasan; M Ruberg; G I Evan; Y Agid; E C Hirsch
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-14       Impact factor: 11.205

4.  Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.

Authors:  J H Kordower; M E Emborg; J Bloch; S Y Ma; Y Chu; L Leventhal; J McBride; E Y Chen; S Palfi; B Z Roitberg; W D Brown; J E Holden; R Pyzalski; M D Taylor; P Carvey; Z Ling; D Trono; P Hantraye; N Déglon; P Aebischer
Journal:  Science       Date:  2000-10-27       Impact factor: 47.728

5.  Adult rat and human bone marrow stromal cells differentiate into neurons.

Authors:  D Woodbury; E J Schwarz; D J Prockop; I B Black
Journal:  J Neurosci Res       Date:  2000-08-15       Impact factor: 4.164

6.  The neuroprotective effects of CGP 3466B in the best in vivo model of Parkinson's disease, the bilaterally MPTP-treated rhesus monkey.

Authors:  G Andringa; A R Cools
Journal:  J Neural Transm Suppl       Date:  2000

7.  CGP 3466 protects dopaminergic neurons in lesion models of Parkinson's disease.

Authors:  P C Waldmeier; W P Spooren; B Hengerer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2000-12       Impact factor: 3.000

8.  Adult bone marrow stromal cells differentiate into neural cells in vitro.

Authors:  J Sanchez-Ramos; S Song; F Cardozo-Pelaez; C Hazzi; T Stedeford; A Willing; T B Freeman; S Saporta; W Janssen; N Patel; D R Cooper; P R Sanberg
Journal:  Exp Neurol       Date:  2000-08       Impact factor: 5.330

9.  Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

Authors:  O Eberhardt; R V Coelln; S Kugler; J Lindenau; S Rathke-Hartlieb; E Gerhardt; S Haid; S Isenmann; C Gravel; A Srinivasan; M Bahr; M Weller; J Dichgans; J B Schulz
Journal:  J Neurosci       Date:  2000-12-15       Impact factor: 6.167

10.  Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease.

Authors:  J H Kordower; S Palfi; E Y Chen; S Y Ma; T Sendera; E J Cochran; E J Cochran; E J Mufson; R Penn; C G Goetz; C D Comella
Journal:  Ann Neurol       Date:  1999-09       Impact factor: 10.422
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  5 in total

1.  Adverse events in total knee arthroplasty: Results of a physician independent survey in 260 patients.

Authors:  Stephan Kirschner; Jörg Lützner; Klaus-Peter Günther; Maria Eberlein-Gonska; Frank Krummenauer
Journal:  Patient Saf Surg       Date:  2010-08-11

Review 2.  Transcranial duplex in the differential diagnosis of parkinsonian syndromes: a systematic review.

Authors:  Annemarie M M Vlaar; Angela Bouwmans; Werner H Mess; Selma C Tromp; Wim E J Weber
Journal:  J Neurol       Date:  2009-02-17       Impact factor: 4.849

3.  Tetrahydroisoquinoline derivatives: a new perspective on monoaminergic dysfunction in children with ADHD?

Authors:  Veit Roessner; Susanne Walitza; Franz Riederer; Regina Hünnerkopf; Aribert Rothenberger; Manfred Gerlach; Andreas Moser
Journal:  Behav Brain Funct       Date:  2007-12-10       Impact factor: 3.759

4.  Meta-analysis of the literature on diagnostic accuracy of SPECT in parkinsonian syndromes.

Authors:  Annemarie M M Vlaar; Marinus J P G van Kroonenburgh; Alfons G H Kessels; Wim E J Weber
Journal:  BMC Neurol       Date:  2007-09-01       Impact factor: 2.474

5.  Protocol of a prospective study on the diagnostic value of transcranial duplex scanning of the substantia nigra in patients with parkinsonian symptoms.

Authors:  Annemarie M M Vlaar; Angela E P Bouwmans; Marinus J P G van Kroonenburgh; Werner H Mess; Selma C Tromp; Piet G W M Wuisman; Alfons G H Kessels; Ania Winogrodzka; Wim E J Weber
Journal:  BMC Neurol       Date:  2007-09-04       Impact factor: 2.474
  5 in total

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