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Literature DB >> 15672142

Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy.

Shuwei Li¹, Nishanth Marthandan, Dawn Bowerman, Harold R Garner, Thomas Kodadek.

Abstract

We report here a strategy for the photolithographic synthesis of diverse, spatially addressable arrays of cyclic peptides which employs a differential deprotection strategy for the combinatorial addition of side chains to a pre-fabricated cyclic core.

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Year: 2005 PMID： 15672142 DOI： 10.1039/b415578e

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

10 in total

1. Protein "fingerprinting" in complex mixtures with peptoid microarrays.

Authors: M Muralidhar Reddy; Thomas Kodadek
Journal: Proc Natl Acad Sci U S A Date: 2005-08-25 Impact factor: 11.205

Review 2. Small-molecule microarrays as tools in ligand discovery.

Authors: Arturo J Vegas; Jason H Fuller; Angela N Koehler
Journal: Chem Soc Rev Date: 2008-05-20 Impact factor: 54.564

Review 3. Contemporary strategies for peptide macrocyclization.

Authors: Christopher J White; Andrei K Yudin
Journal: Nat Chem Date: 2011-06-23 Impact factor: 24.427

4. Synthesis of bis-peptides attached on poly[n]norbornene molecular scaffolds with well-defined relative positions and distances.

Authors: Muhong Shang; Ronald N Warrener; Douglas N Butler; Yasujiro Murata; Davor Margetić
Journal: Mol Divers Date: 2010-09-21 Impact factor: 2.943

Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy.

1. Protein "fingerprinting" in complex mixtures with peptoid microarrays.

Review 2. Small-molecule microarrays as tools in ligand discovery.

Review 3. Contemporary strategies for peptide macrocyclization.

4. Synthesis of bis-peptides attached on poly[n]norbornene molecular scaffolds with well-defined relative positions and distances.

5. Towards vast libraries of scaffold-diverse, conformationally constrained oligomers.

6. Encoded combinatorial libraries for the construction of cyclic peptoid microarrays.

7. A scalable method for multiplex LED-controlled synthesis of DNA in capillaries.

8. High-resolution mapping of linear antibody epitopes using ultrahigh-density peptide microarrays.

9. Identification and mapping of linear antibody epitopes in human serum albumin using high-density Peptide arrays.

10. Cell-permeable bicyclic peptide inhibitors against intracellular proteins.