Literature DB >> 15669113

Comparison of the immunogenicity of recombinant VP2 and VP3 of infectious pancreatic necrosis virus and marine birnavirus.

C H Moon1, J W Do, S J Cha, J D Bang, M A Park, D J Yoo, J M Lee, H G Kim, D K Chung, J W Park.   

Abstract

Recombinant proteins of truncated viral protein-2 (VP2) (aa 79-359) and VP3 of infectious pancreatic necrosis virus (IPNV) and marine birnavirus (MABV) were expressed in E. coli and their immunogenicities in fish were investigated. The recombinant proteins from IPNV were used to immunize rainbow trout and those from MABV to immunize flounder. The sera from the immunized fishes were assayed for antibody by ELISA and a neutralization test. Both the recombinant VP2 and VP3 produced antibodies in fish but the VP3 antibody titers were higher than that of the VP2 of IPNV and MABV. These results indicate that the recombinant VP3 is more immunogenic than the recombinant VP2.

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Year:  2004        PMID： 15669113     DOI： 10.1007/s00705-004-0339-2

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  4 in total

1.  Identification and functional analysis of salmon annexin 1 induced by a virus infection in a fish cell line.

Authors:  Hyun Jin Hwang; Chang Hoon Moon; Han Geun Kim; Joo Yun Kim; Jung Min Lee; Jeong Woo Park; Dae Kyun Chung
Journal:  J Virol       Date:  2007-09-19       Impact factor: 5.103

2.  Sequence analysis of infectious pancreatic necrosis virus isolated from Iranian reared rainbow trout (Oncorhynchus mykiss) in 2012.

Authors:  Maryam Dadar; Rahim Peyghan; Hamid Rajabi Memari; Masod Reza Seifi Abad Shapouri; Reza Hasanzadeh; Laleh Moazzami Goudarzi; Vikram N Vakharia
Journal:  Virus Genes       Date:  2013-09-19       Impact factor: 2.332

3.  A polyprotein-expressing salmonid alphavirus replicon induces modest protection in atlantic salmon (Salmo salar) against infectious pancreatic necrosis.

Authors:  Azila Abdullah; Christel M Olsen; Kjartan Hodneland; Espen Rimstad
Journal:  Viruses       Date:  2015-01-19       Impact factor: 5.048

4.  Bivalent DNA vaccine induces significant immune responses against infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus in rainbow trout.

Authors:  Liming Xu; Jingzhuang Zhao; Miao Liu; Guangming Ren; Feng Jian; Jiasheng Yin; Ji Feng; Hongbai Liu; Tongyan Lu
Journal:  Sci Rep       Date:  2017-07-18       Impact factor: 4.379
  4 in total

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