Literature DB >> 15668105

DNA adduction and mutagenic properties of acrylamide.

Ahmad Besaratinia1, Gerd P Pfeifer.   

Abstract

This review article summarizes our current knowledge on DNA damaging and mutagenic properties of acrylamide. Direct and indirect modes of interaction of acrylamide with DNA are discussed, and the resulting alkylating DNA adducts are highlighted. Emphasis is placed on glycidamide-DNA adducts generated via epoxidation of acrylamide presumably by cytochrome P4502E1. Dosimetry and mapping of acrylamide-induced DNA adducts in vitro and/or in vivo are described. Mutagenic potency and specificity of acrylamide in relation to its respective DNA adducts are discussed. Prospective views are provided on the potential applications of acrylamide-induced DNA adduct dosimetry/mapping and mutation frequency/spectrometry for biomonitoring purposes.

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Year:  2005        PMID： 15668105     DOI： 10.1016/j.mrgentox.2004.10.011

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  10 in total

1.  Biological monitoring for occupational acrylamide exposure from acrylamide production workers.

Authors:  Yu-Fang Huang; Kuen-Yuh Wu; Saou-Hsing Liou; Shi-Nian Uang; Chu-Chih Chen; Wei-Chung Shih; Shih-Chuan Lee; Chih-Chun Jean Huang; Mei-Lien Chen
Journal:  Int Arch Occup Environ Health       Date:  2010-07-02       Impact factor: 3.015

2.  Tumorigenicity of acrylamide and its metabolite glycidamide in the neonatal mouse bioassay.

Authors:  Linda S Von Tungeln; Daniel R Doerge; Gonçalo Gamboa da Costa; M Matilde Marques; William M Witt; Igor Koturbash; Igor P Pogribny; Frederick A Beland
Journal:  Int J Cancer       Date:  2012-03-28       Impact factor: 7.396

3.  Acrylamide Production in Autoclaved Rodent Feed.

Authors:  David M Kurtz; Rallene Glascoe; Gordon Caviness; Jacqueline Locklear; Tanya Whiteside; Toni Ward; Floyd Adsit; Fred Lih; Leesa J Deterding; Mona I Churchwell; Daniel R Doerge; Grace E Kissling
Journal:  J Am Assoc Lab Anim Sci       Date:  2018-10-25       Impact factor: 1.232

4.  Evaluation of cII gene mutation in the brains of Big Blue mice exposed to acrylamide and glycidamide in drinking water.

Authors:  Hai-Fang Li; Sharon D Shelton; Todd A Townsend; Nan Mei; Mugimane G Manjanatha
Journal:  J Toxicol Sci       Date:  2016       Impact factor: 2.196

5.  Is Acrylamide as Harmful as We Think? A New Look at the Impact of Acrylamide on the Viability of Beneficial Intestinal Bacteria of the Genus Lactobacillus.

Authors:  Katarzyna Petka; Tomasz Tarko; Aleksandra Duda-Chodak
Journal:  Nutrients       Date:  2020-04-21       Impact factor: 5.717

6.  Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans.

Authors:  Maria Zhivagui; Alvin W T Ng; Maude Ardin; Mona I Churchwell; Manuraj Pandey; Claire Renard; Stephanie Villar; Vincent Cahais; Alexis Robitaille; Liacine Bouaoun; Adriana Heguy; Kathryn Z Guyton; Martha R Stampfer; James McKay; Monica Hollstein; Magali Olivier; Steven G Rozen; Frederick A Beland; Michael Korenjak; Jiri Zavadil
Journal:  Genome Res       Date:  2019-03-07       Impact factor: 9.043

7.  Analysis of Acrylamide and Glycidamide in Dried Blood Spot of Smokers Using Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry.

Authors:  Yahdiana Harahap; Afaf Amma Lahilla; Anastasia Sharon Jautan; Amiral Hafidz; Sunarsih Sunarsih
Journal:  Drug Des Devel Ther       Date:  2022-02-28       Impact factor: 4.162

Review 8.  Acrylamide Neurotoxicity as a Possible Factor Responsible for Inflammation in the Cholinergic Nervous System.

Authors:  Marta Kopańska; Anna Łagowska; Barbara Kuduk; Agnieszka Banaś-Ząbczyk
Journal:  Int J Mol Sci       Date:  2022-02-12       Impact factor: 5.923

9.  Time Trends of Acrylamide Exposure in Europe: Combined Analysis of Published Reports and Current HBM4EU Studies.

Authors:  Michael Poteser; Federica Laguzzi; Thomas Schettgen; Nina Vogel; Till Weber; Philipp Zimmermann; Domenica Hahn; Marike Kolossa-Gehring; Sónia Namorado; An Van Nieuwenhuyse; Brice Appenzeller; Thórhallur I Halldórsson; Ása Eiríksdóttir; Line Småstuen Haug; Cathrine Thomsen; Fabio Barbone; Valentina Rosolen; Loïc Rambaud; Margaux Riou; Thomas Göen; Stefanie Nübler; Moritz Schäfer; Karin Haji Abbas Zarrabi; Liese Gilles; Laura Rodriguez Martin; Greet Schoeters; Ovnair Sepai; Eva Govarts; Hanns Moshammer
Journal:  Toxics       Date:  2022-08-17

10.  Effects of acrylamide on the activity and structure of human brain creatine kinase.

Authors:  Qing Sheng; He-Chang Zou; Zhi-Rong Lü; Fei Zou; Yong-Doo Park; Yong-Bin Yan; Shan-Jing Yao
Journal:  Int J Mol Sci       Date:  2009-11-20       Impact factor: 6.208
  10 in total

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