| Literature DB >> 15664856 |
Jonathan D Gough1, Watson J Lees.
Abstract
PDI is an enzyme that acts as a chaperone, shufflase, and oxidase during the folding of disulfide-containing proteins. The ability of aromatic thiols to increase the activity of PDI-catalyzed protein folding over that of the standard thiol glutathione (GSH) was measured. 4-Mercaptobenzoic acid (ArSH) increased the activity of PDI by a factor of three.Entities:
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Year: 2005 PMID： 15664856 DOI： 10.1016/j.bmcl.2004.11.005
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823