Literature DB >> 15664747

Simultaneous quantification of 12 bioactive components of Ligusticum chuanxiong Hort. by high-performance liquid chromatography.

Ru Yan1, Song-Lin Li, Hoi-Sing Chung, Yun-Kau Tam, Ge Lin.   

Abstract

A sensitive and specific HPLC-UV method has been developed, for the first time, to simultaneously quantify 12 bioactive ingredients in Ligusticum chuanxiong Hort. (Rhizoma Chuanxiong). This assay was fully validated in respect to precision, accuracy and sensitivity. This method was successfully applied to quantify twelve ingredients in six different Chuanxiong samples. The results demonstrated significant variations in the total content and quantity of each of the main bioactive compounds in different herbs, indicating that quality control of bioactive ingredients in Chuanxiong is critical to ensure its clinical benefits. This assay can be readily utilized as quality control method for Chuanxiong.

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Year:  2005        PMID： 15664747     DOI： 10.1016/j.jpba.2004.09.054

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN： 0731-7085            Impact factor:   3.935


  9 in total

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Journal:  J Anal Methods Chem       Date:  2019-11-22       Impact factor: 2.193
  9 in total

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