AIM: Sacral chordoma is a primarily benign tumor with a high tendency to recur. A correct definition of tumor volume is a significant prognostic factor. We compared the value of CT and MRI in diagnosing a sacral chordoma. METHODS: 31 patients with a histologically proven sacral chordoma were included in this study. Following parameters were analyzed by two independent radiologists: septation, signs of blood and ossification in the tumor tissue, contrast enhancement, maximal tumor diameter, infiltration of the soft tissue, the dural salc and the cauda equina and multifocality. RESULTS: In CT all chordomas showed a hypodensity to the normal tissue and in MRI a hyperintensity on T2w images with a low level of contrast enhancement. On the basis of the more precise soft tissue contrast of MRI compared with CT, MRI was significantly more accurate in all tested parameters (p <0.05) besides in detecting tumor ossification. In CT tumor volume was frequently underestimated. CONCLUSION: MRI in sacral chordoma is an essential tool in the pretherapeutic diagnostic regimen and in a state of relapse.
AIM: Sacral chordoma is a primarily benign tumor with a high tendency to recur. A correct definition of tumor volume is a significant prognostic factor. We compared the value of CT and MRI in diagnosing a sacral chordoma. METHODS: 31 patients with a histologically proven sacral chordoma were included in this study. Following parameters were analyzed by two independent radiologists: septation, signs of blood and ossification in the tumor tissue, contrast enhancement, maximal tumor diameter, infiltration of the soft tissue, the dural salc and the cauda equina and multifocality. RESULTS: In CT all chordomas showed a hypodensity to the normal tissue and in MRI a hyperintensity on T2w images with a low level of contrast enhancement. On the basis of the more precise soft tissue contrast of MRI compared with CT, MRI was significantly more accurate in all tested parameters (p <0.05) besides in detecting tumor ossification. In CT tumor volume was frequently underestimated. CONCLUSION: MRI in sacral chordoma is an essential tool in the pretherapeutic diagnostic regimen and in a state of relapse.
Authors: G Sze; L S Uichanco; M N Brant-Zawadzki; R L Davis; P H Gutin; C B Wilson; D Norman; T H Newton Journal: Radiology Date: 1988-01 Impact factor: 11.105
Authors: Daniela Schulz-Ertner; Thomas Haberer; Oliver Jäkel; Christoph Thilmann; Michael Krämer; Wolfgang Enghardt; Gerhard Kraft; Michael Wannenmacher; Jürgen Debus Journal: Int J Radiat Oncol Biol Phys Date: 2002-05-01 Impact factor: 7.038
Authors: Christoph Thilmann; Daniela Schulz-Ertner; Angelika Zabel; Klaus K Herfarth; Michael Wannenmacher; Jürgen Debus Journal: Acta Oncol Date: 2002 Impact factor: 4.089