BACKGROUND: The exclusion of brain metastasis is important to determine the optimal treatment plan in patients with non-small cell lung cancer (NSCLC). However, a routine examination using magnetic resonance imaging (MRI) for the brain remains controversial in preoperative patients with resectable disease. METHODS: To assess the necessity of routine brain MRI for preoperative patients, a retrospective analysis for a consecutive series of 338 patients with NSCLC was performed. Among the 338 patients, 141 patients who were considered to have potentially resectable diseases through an examination of the chest plus an upper abdominal computed tomography scan and bone radioisotope scan with no neurological symptoms received MRI for examination of brain metastasis. RESULTS: The incidence of brain metastasis detected by MRI was 2.1% (three of 141) in all patients, 0% (zero of 80) in patients with N0 disease, 5.2% (one of 19) in N1, and 4.7% (two of 42) in N2 cases. CONCLUSION: In patients with resectable NSCLC, a brain MRI is not considered to be useful due to the low incidence of asymptomatic brain metastasis.
BACKGROUND: The exclusion of brain metastasis is important to determine the optimal treatment plan in patients with non-small cell lung cancer (NSCLC). However, a routine examination using magnetic resonance imaging (MRI) for the brain remains controversial in preoperative patients with resectable disease. METHODS: To assess the necessity of routine brain MRI for preoperative patients, a retrospective analysis for a consecutive series of 338 patients with NSCLC was performed. Among the 338 patients, 141 patients who were considered to have potentially resectable diseases through an examination of the chest plus an upper abdominal computed tomography scan and bone radioisotope scan with no neurological symptoms received MRI for examination of brain metastasis. RESULTS: The incidence of brain metastasis detected by MRI was 2.1% (three of 141) in all patients, 0% (zero of 80) in patients with N0 disease, 5.2% (one of 19) in N1, and 4.7% (two of 42) in N2 cases. CONCLUSION: In patients with resectable NSCLC, a brain MRI is not considered to be useful due to the low incidence of asymptomatic brain metastasis.
Authors: Luis Filipe Azenha; Pietro Bertoglio; Peter Kestenholz; Michel Gonzalez; Matyas Pal; Thorsten Krueger; Bassam Redwan; Volkan Koesek; Eyad Al Masri; Takuro Miyazaki; Farahnaz Sadegh Beigee; Benedetta Bedetti; Philipp Schnorr; Joachim Schmidt; Patrick Zardo; Laura Boschetti; Sven Oliver Schumann; Fabrizio Minervini Journal: Cancers (Basel) Date: 2022-05-13 Impact factor: 6.575
Authors: Leah M Backhus; Farhood Farjah; Thomas K Varghese; Aaron M Cheng; Xiao-Hua Zhou; Douglas E Wood; Larry Kessler; Steven B Zeliadt Journal: J Clin Oncol Date: 2014-09-22 Impact factor: 44.544
Authors: Ali G Saad; Beow Y Yeap; Frederik B J M Thunnissen; Geraldine S Pinkus; Jack L Pinkus; Massimo Loda; David J Sugarbaker; Bruce E Johnson; Lucian R Chirieac Journal: Cancer Date: 2008-10-15 Impact factor: 6.860