| Literature DB >> 15652472 |
Abstract
SR proteins serve multiple roles in the posttranscriptional control of gene expression, including as regulators of alternative splicing. In this issue of Cell, Xu et al. (2005) demonstrate that a heart-specific knockout of one SR protein, ASF/SF2, produces cardiomyopathy and misregulation of specific alternative splicing events during early postnatal development.Entities:
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Year: 2005 PMID: 15652472 DOI: 10.1016/j.cell.2004.12.030
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582