| Literature DB >> 15652364 |
Esvet Akbas1, Ismet Berber, Ahmet Sener, Beybala Hasanov.
Abstract
Some new 1H-pyrazole-3-carboxylic acid and pyridazinone derivatives were synthesized and evaluated for their antibacterial activities against Bacillus cereus ATCC 7064, Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 4230 and Pseudomonas putida using tube dilution method. The minimal inhibitory concentrations (MICs) experiments revealed that all chemical compounds showed inhibitor effects on the growth of the test microorganisms. Moreover, the results of this research showed that the compound named as 5c was the best compound in the series, exhibiting antibacterial activity against both Gram-positive and Gram-negative bacteria.Entities:
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Year: 2004 PMID： 15652364 DOI： 10.1016/j.farmac.2004.09.003
Source DB: PubMed Journal: Farmaco ISSN： 0014-827X