Literature DB >> 15651620

Dosimetric characteristics of the Leipzig surface applicators used in the high dose rate brachy radiotherapy.

Hongquan Niu1, Wen C Hsi, James C H Chu, Michael C Kirk, Erik Kouwenhoven.   

Abstract

The nucletron Leipzig applicator is designed for (HDR) 192Ir brachy radiotherapy of surface lesions. The dosimetric characteristics of this applicator were investigated using simulation method based on Monte Carlo N-particle (MCNP) code and phantom measurements. The simulation method was validated by comparing calculated dose rate distributions of nucletron microSelectron HDR 192Ir source against published data. Radiochromic films and metal-oxide-semiconductor field-effect transistor (MOSFET) detectors were used for phantom measurements. The double exposure technique, correcting the nonuniform film sensitivity, was applied in the film dosimetry. The linear fit of multiple readings with different irradiation times performed for each MOSFET detector measurement was used to obtain the dose rate of each measurement and to correct the source transit-time error. The film and MOSFET measurements have uncertainties of 3%-7% and 3%-5%, respectively. The dose rate distributions of the Leipzig applicator with 30 mm opening calculated by the validated MC method were verified by measurements of film and MOSFET detectors. Calculated two-dimensional planar dose rate distributions show similar patterns as the film measurement. MC calculated dose rate at a reference point defined at depth 5 mm on the applicator's central axis is 7% lower than the film and 3% higher than the MOSFET measurements. The dose rate of a Leipzig applicator with 30 mm opening at reference point is 0.241+/-3% cGy h(-1) U(-1). The MC calculated depth dose rates and profiles were tabulated for clinic use.

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Year:  2004        PMID: 15651620     DOI: 10.1118/1.1812609

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  13 in total

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2.  The initial experience of electronic brachytherapy for the treatment of non-melanoma skin cancer.

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4.  Depth determination of skin cancers treated with superficial brachytherapy: ultrasound vs. histopathology.

Authors:  Rosa Ballester-Sánchez; Olga Pons-Llanas; Margarita Llavador-Ros; Rafael Botella-Estrada; Antonio Ballester-Cuñat; Alejandro Tormo-Micó; Francisco Javier Celadá-Álvarez; Silvia Rodríguez-Villalba; Manuel Santos-Ortega; Facundo Ballester-Pallarés; Jose Perez-Calatayud
Journal:  J Contemp Brachytherapy       Date:  2014-12-31

5.  A pilot study of ultrasound-guided electronic brachytherapy for skin cancer.

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Journal:  J Contemp Brachytherapy       Date:  2015-10-30

6.  Dosimetric evaluation of internal shielding in a high dose rate skin applicator.

Authors:  Françoise Lliso; Domingo Granero; Jose Perez-Calatayud; Vicente Carmona; M Carmen Pujades; Facundo Ballester
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Review 7.  Non-melanoma skin cancer treated with high-dose-rate brachytherapy: a review of literature.

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Journal:  J Contemp Brachytherapy       Date:  2016-12-02

8.  Non-melanoma skin cancer treated with HDR Valencia applicator: clinical outcomes.

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9.  Non-melanoma skin cancer treated with high-dose-rate brachytherapy and Valencia applicator in elderly patients: a retrospective case series.

Authors:  Durim Delishaj; Concetta Laliscia; Bruno Manfredi; Stefano Ursino; Francesco Pasqualetti; Ezio Lombardo; Franco Perrone; Riccardo Morganti; Fabiola Paiar; Maria Grazia Fabrini
Journal:  J Contemp Brachytherapy       Date:  2015-11-23

10.  Evaluation of treatment plans using various treatment techniques for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of feet.

Authors:  Jong Min Park; Il Han Kim; Sung-Joon Ye; Kyubo Kim
Journal:  J Appl Clin Med Phys       Date:  2014-11-08       Impact factor: 2.102

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