| Literature DB >> 15650260 |
Robert M Strieter1, John A Belperio, Marie D Burdick, Sherven Sharma, Steven M Dubinett, Michael P Keane.
Abstract
CXC chemokines have been found to be important in the regulation of angiogenesis and tumor-related immunity, and in promoting organ-specific metastases. This review highlights the importance of CXC chemokine ligands and receptors in mediating non-small cell lung cancer tumor-associated angiogenesis, "immunoangiostasis," and organ-specific metastases. These findings may ultimately lead to clinical strategies to target CXC chemokines in non-small cell lung cancer.Entities:
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Year: 2004 PMID: 15650260 DOI: 10.1196/annals.1322.041
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN: 0077-8923 Impact factor: 5.691