Ronald Klein1, Barbara E K Klein, Scot E Moss. 1. Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, 610 North Walnut Street, 4th Floor WARF, Madison, WI 53726-2336, USA. kleinr@epi.ophth.wise.edu
Abstract
OBJECTIVE: The purpose of this report is to examine the overall 10-year incidence of erectile dysfunction and its relationships to other characteristics in men with younger onset diabetes. METHODS: In a population-based cohort study in southern Wisconsin, a 10-year cumulative incidence of reported erectile dysfunction was obtained in men who were 21 years of age or older, were less than 30 years of age at diagnosis of diabetes, had 10 or more years of diabetes, and were taking insulin (n=264). RESULTS: Twenty-five percent developed erectile dysfunction. The incidence of erectile dysfunction increased with age (from 10.2% in those 21-29 years of age to 48.6% in those 40 years of age or older, P<.0001) and with increasing duration of diabetes (from 16.0% in those with 11-14 years of diabetes at baseline to 38.2% in those with 25 or more years of diabetes, P=.01). In multivariate analyses, incidence of erectile dysfunction was associated with age [odds ratio (OR) 1.10, 95% confidence interval (CI), 1.06, 1.14], untreated hypertension (OR 5.01, 95% CI, 2.05, 12.27), and a history of smoking (OR 2.41, 95% CI, 1.09, 5.30) at baseline. CONCLUSIONS: These data suggest that cessation of cigarette smoking and tighter control of blood pressure might prevent or delay the onset of erectile dysfunction in persons with type 1 diabetes.
OBJECTIVE: The purpose of this report is to examine the overall 10-year incidence of erectile dysfunction and its relationships to other characteristics in men with younger onset diabetes. METHODS: In a population-based cohort study in southern Wisconsin, a 10-year cumulative incidence of reported erectile dysfunction was obtained in men who were 21 years of age or older, were less than 30 years of age at diagnosis of diabetes, had 10 or more years of diabetes, and were taking insulin (n=264). RESULTS: Twenty-five percent developed erectile dysfunction. The incidence of erectile dysfunction increased with age (from 10.2% in those 21-29 years of age to 48.6% in those 40 years of age or older, P<.0001) and with increasing duration of diabetes (from 16.0% in those with 11-14 years of diabetes at baseline to 38.2% in those with 25 or more years of diabetes, P=.01). In multivariate analyses, incidence of erectile dysfunction was associated with age [odds ratio (OR) 1.10, 95% confidence interval (CI), 1.06, 1.14], untreated hypertension (OR 5.01, 95% CI, 2.05, 12.27), and a history of smoking (OR 2.41, 95% CI, 1.09, 5.30) at baseline. CONCLUSIONS: These data suggest that cessation of cigarette smoking and tighter control of blood pressure might prevent or delay the onset of erectile dysfunction in persons with type 1 diabetes.
Authors: Aruna V Sarma; James M Hotaling; Ian H de Boer; Rodney L Dunn; Mary K Oerline; Karandeep Singh; Jack Goldberg; Alan Jacobson; Barbara Braffett; William H Herman; Rodica Pop-Busui; Hunter Wessells Journal: J Hypertens Date: 2019-05 Impact factor: 4.844
Authors: Melody R Palmer; Sarah K Holt; Aruna V Sarma; Rodney L Dunn; James M Hotaling; Patricia A Cleary; Barbara H Braffett; Catherine Martin; William H Herman; Alan M Jacobson; Hunter Wessells Journal: J Sex Med Date: 2017-08-26 Impact factor: 3.802
Authors: Hunter Wessells; David F Penson; Patricia Cleary; Brandy N Rutledge; John M Lachin; Kevin T McVary; David S Schade; Aruna V Sarma Journal: J Urol Date: 2011-03-21 Impact factor: 7.450
Authors: Mikołaj Kamiński; Michał Kulecki; Paweł Lachowski; Dominika Kasprzak; Ania Kulczycka; Maria Kozłowska; Daria Klause; Aleksandra Uruska; Mateusz Michalski; Dorota Zozulińska-Ziółkiewicz Journal: Int J Angiol Date: 2022-01-13
Authors: Giovanni Corona; Andrea M Isidori; Antonio Aversa; Marco Bonomi; Alberto Ferlin; Carlo Foresta; Sandro La Vignera; Mario Maggi; Rosario Pivonello; Linda Vignozzi; Francesco Lombardo Journal: Rev Endocr Metab Disord Date: 2020-03 Impact factor: 6.514
Authors: Sara J Turek; Stephanie M Hastings; Jennifer K Sun; George L King; Hillary A Keenan Journal: Diabetes Care Date: 2013-06-18 Impact factor: 19.112