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Literature DB >> 15642360

The biosynthetic routes for carbon monoxide and cyanide in the Ni-Fe active site of hydrogenases are different.

Winfried Roseboom¹, Melanie Blokesch, August Böck, Simon P J Albracht.

Abstract

The incorporation of carbon into the carbon monoxide and cyanide ligands of [NiFe]-hydrogenases has been investigated by using (13)C labelling in infrared studies of the Allochromatium vinosum enzyme and by (14)C labelling experiments with overproduced Hyp proteins from Escherichia coli. The results suggest that the biosynthetic routes of the carbon monoxide and cyanide ligands in [NiFe]-hydrogenases are different.

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Year: 2005 PMID： 15642360 DOI： 10.1016/j.febslet.2004.12.013

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

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Cited

13 in total

1. Crystallization and preliminary X-ray crystallographic analysis of the [NiFe]-hydrogenase maturation factor HypF1 from Ralstonia eutropha H16.

Authors: Gordon Winter; Simon Dökel; Anne K Jones; Patrick Scheerer; Norbert Krauss; Wolfgang Höhne; Bärbel Friedrich
Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun Date: 2010-03-31

2. Structural basis for the reaction mechanism of S-carbamoylation of HypE by HypF in the maturation of [NiFe]-hydrogenases.

Authors: Yasuhito Shomura; Yoshiki Higuchi
Journal: J Biol Chem Date: 2012-06-27 Impact factor: 5.157

The biosynthetic routes for carbon monoxide and cyanide in the Ni-Fe active site of hydrogenases are different.

1. Crystallization and preliminary X-ray crystallographic analysis of the [NiFe]-hydrogenase maturation factor HypF1 from Ralstonia eutropha H16.

2. Structural basis for the reaction mechanism of S-carbamoylation of HypE by HypF in the maturation of [NiFe]-hydrogenases.

3. Proteolytic cleavage orchestrates cofactor insertion and protein assembly in [NiFe]-hydrogenase biosynthesis.

4. Probing the origin of the metabolic precursor of the CO ligand in the catalytic center of [NiFe] hydrogenase.

5. A universal scaffold for synthesis of the Fe(CN)2(CO) moiety of [NiFe] hydrogenase.

6. Structure of [NiFe] hydrogenase maturation protein HypE from Escherichia coli and its interaction with HypF.

7. Functional studies of [FeFe] hydrogenase maturation in an Escherichia coli biosynthetic system.

8. Interaction between hydrogenase maturation factors HypA and HypB is required for [NiFe]-hydrogenase maturation.

9. Structural basis for GTP-dependent dimerization of hydrogenase maturation factor HypB.

10. Dual role of HupF in the biosynthesis of [NiFe] hydrogenase in Rhizobium leguminosarum.