Literature DB >> 15630571

[Pancreatic ductal adenocarcinoma and its precursors].

J Lüttges1, G Klöppel.   

Abstract

Pancreatic ductal adenocarcinoma is the most frequent malignant pancreatic tumor. It is one of the tumors that has a particularly poor prognosis. Its morphological characteristics are: preferential localization in the head of the pancreas, ductal-glandular tumor structures combined with marked desmoplasia and CEA and MUC1 positivity. Variants of this carcinoma include adenosquamous carcinomas, undifferentiated pleomorphic carcinomas and mixed ductal-endocrine tumors. With the definition of ductal lesions as pancreatic intraepithelial neoplasia, a progression model for pancreatic ductal carcinoma has been developed and corresponding gene alterations have been detected.

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Year:  2005        PMID： 15630571     DOI： 10.1007/s00292-004-0735-0

Source DB:  PubMed          Journal:  Pathologe        ISSN： 0172-8113            Impact factor:   1.011


  29 in total

1.  Gene expression profiles of microdissected pancreatic ductal adenocarcinoma.

Authors:  Robert Grützmann; Melanie Foerder; Ingo Alldinger; Eike Staub; Thomas Brümmendorf; Stefan Röpcke; Xinzhong Li; Glen Kristiansen; Ralf Jesenofsky; Ralf Jesnowski; Bence Sipos; Matthias Löhr; Jutta Lüttges; Detlef Ockert; Günter Klöppel; Hans Detlev Saeger; Christian Pilarsky
Journal:  Virchows Arch       Date:  2003-08-27       Impact factor: 4.064

Review 2.  Ki-ras oncogene mutations in chronic pancreatitis: which discriminating ability for malignant potential?

Authors:  J L van Laethem
Journal:  Ann N Y Acad Sci       Date:  1999-06-30       Impact factor: 5.691

3.  Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions.

Authors:  R H Hruban; N V Adsay; J Albores-Saavedra; C Compton; E S Garrett; S N Goodman; S E Kern; D S Klimstra; G Klöppel; D S Longnecker; J Lüttges; G J Offerhaus
Journal:  Am J Surg Pathol       Date:  2001-05       Impact factor: 6.394

Review 4.  An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms.

Authors:  Ralph H Hruban; Kyoichi Takaori; David S Klimstra; N Volkan Adsay; Jorge Albores-Saavedra; Andrew V Biankin; Sandra A Biankin; Carolyn Compton; Noriyoshi Fukushima; Toru Furukawa; Michael Goggins; Yo Kato; Gunter Klöppel; Daniel S Longnecker; Jutta Lüttges; Anirban Maitra; G Johan A Offerhaus; Michio Shimizu; Suguru Yonezawa
Journal:  Am J Surg Pathol       Date:  2004-08       Impact factor: 6.394

Review 5.  The pathology of ductal-type pancreatic carcinomas and pancreatic intraepithelial neoplasia: insights for clinicians.

Authors:  Günter Klöppel; Jutta Lüttges
Journal:  Curr Gastroenterol Rep       Date:  2004-04

Review 6.  Epidemiology and risk factors in pancreatic cancer.

Authors:  J D Ahlgren
Journal:  Semin Oncol       Date:  1996-04       Impact factor: 4.929

7.  Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group.

Authors:  A B Lowenfels; P Maisonneuve; G Cavallini; R W Ammann; P G Lankisch; J R Andersen; E P Dimagno; A Andrén-Sandberg; L Domellöf
Journal:  N Engl J Med       Date:  1993-05-20       Impact factor: 91.245

8.  Morphological lesions associated with human primary invasive nonendocrine pancreas cancer.

Authors:  A L Cubilla; P J Fitzgerald
Journal:  Cancer Res       Date:  1976-07       Impact factor: 12.701

9.  BRCA2 germline mutations in familial pancreatic carcinoma.

Authors:  Stephan A Hahn; Bill Greenhalf; Ian Ellis; Mercedes Sina-Frey; Harald Rieder; Birgit Korte; Berthold Gerdes; Ralf Kress; Andreas Ziegler; John A Raeburn; Donata Campra; Robert Grützmann; Helga Rehder; Matthias Rothmund; Wolff Schmiegel; John P Neoptolemos; Detlef K Bartsch
Journal:  J Natl Cancer Inst       Date:  2003-02-05       Impact factor: 13.506

10.  Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays.

Authors:  Christine A Iacobuzio-Donahue; Anirban Maitra; Mari Olsen; Anson W Lowe; N Tjarda van Heek; Christophe Rosty; Kim Walter; Norihiro Sato; Antony Parker; Raheela Ashfaq; Elizabeth Jaffee; Byungwoo Ryu; Jessa Jones; James R Eshleman; Charles J Yeo; John L Cameron; Scott E Kern; Ralph H Hruban; Patrick O Brown; Michael Goggins
Journal:  Am J Pathol       Date:  2003-04       Impact factor: 4.307
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  4 in total

1.  Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation.

Authors:  Lisa D Mills; Yaqing Zhang; Ronald J Marler; Marta Herreros-Villanueva; Lizhi Zhang; Luciana L Almada; Fergus Couch; Cynthia Wetmore; Marina Pasca di Magliano; Martin E Fernandez-Zapico
Journal:  J Biol Chem       Date:  2013-03-12       Impact factor: 5.157

Review 2.  Hepatocyte Growth Factor from a Clinical Perspective: A Pancreatic Cancer Challenge.

Authors:  Wasia Rizwani; Amanda E Allen; Jose G Trevino
Journal:  Cancers (Basel)       Date:  2015-09-03       Impact factor: 6.639

3.  Inflammation Associated Pancreatic Tumorigenesis: Upregulation of Succinate Dehydrogenase (Subunit B) Reduces Cell Growth of Pancreatic Ductal Epithelial Cells.

Authors:  Sascha Rahn; Philippe Dänzer Barbosa; Julia Luisa Möller; Nourhane Ammar; Tobias Demetrowitsch; Ole Helm; Daniela Wesch; Bence Sipos; Christoph Röcken; Karin Schwarz; Heiner Schäfer; Susanne Sebens
Journal:  Cancers (Basel)       Date:  2019-12-21       Impact factor: 6.639

4.  Clinicopathological and Prognostic Value of Survivin Expression in Surgically Resected Pancreatic Ductal Adenocarcinoma.

Authors:  Christian Vay; Shahrooz Babaei; Sami-Alexander Safi; Levent Dizdar; Alexander Rehders; Lena Haeberle; Christoph Roderburg; Sven H Loosen; Irene Esposito; Wolfram T Knoefel; Andreas Krieg
Journal:  Cancers (Basel)       Date:  2022-07-18       Impact factor: 6.575
  4 in total

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