OBJECTIVES: The aim of our study was to evaluate the diagnostic accuracy of 16-multi-detector spiral computed tomography (MDCT) with 188 ms temporal resolution. BACKGROUND: Because of rapid technical innovations, MDCT coronary imaging has significantly improved in the last five years. Recent results indicate a high diagnostic accuracy, especially in patients with clinical suspicion of coronary artery disease (CAD). METHODS: A total of 72 consecutive patients (30 women, 42 men, age 64 +/- 10 years) scheduled for invasive coronary angiography (ICA) because of suspected CAD were additionally studied by MDCT (Sensation 16 Speed 4D, Siemens, Forchheim, Germany). Thirty-seven of 72 patients (51%) received an additional beta-blockade before MDCT because of heart rates >65 beats/min. The MDCT scans were analyzed regarding the presence of coronary artery lesions. Results were compared with ICA. RESULTS: All 72 scans showed diagnostic image quality (heart rate: 64.1 +/- 9.2 beats/min, calcium mass: 86 +/- 156 mg). Thirteen coronary segments were evaluated in each patient. Sixty-two of 936 (6.6%) segments showed a nondiagnostic image quality. All segments were included in the analysis. A total of 117 relevant lesions (diameter stenosis >50%) were detected using ICA, and 96 of 117 (82%) were detected by MDCT. Sensitivity, specificity, and positive and negative predictive values for the whole study group were as follows: 82%, 98%, 87%, and 97%, respectively. The correct clinical diagnosis of presence or absence of significant CAD was obtained in 65 of 72 (90%) patients. All stenoses were detected by MDCT in 52 of 72 (72%) patients. CONCLUSIONS: Our results indicate a high diagnostic accuracy of 16-slice MDCT with improved temporal resolution.
OBJECTIVES: The aim of our study was to evaluate the diagnostic accuracy of 16-multi-detector spiral computed tomography (MDCT) with 188 ms temporal resolution. BACKGROUND: Because of rapid technical innovations, MDCT coronary imaging has significantly improved in the last five years. Recent results indicate a high diagnostic accuracy, especially in patients with clinical suspicion of coronary artery disease (CAD). METHODS: A total of 72 consecutive patients (30 women, 42 men, age 64 +/- 10 years) scheduled for invasive coronary angiography (ICA) because of suspected CAD were additionally studied by MDCT (Sensation 16 Speed 4D, Siemens, Forchheim, Germany). Thirty-seven of 72 patients (51%) received an additional beta-blockade before MDCT because of heart rates >65 beats/min. The MDCT scans were analyzed regarding the presence of coronary artery lesions. Results were compared with ICA. RESULTS: All 72 scans showed diagnostic image quality (heart rate: 64.1 +/- 9.2 beats/min, calcium mass: 86 +/- 156 mg). Thirteen coronary segments were evaluated in each patient. Sixty-two of 936 (6.6%) segments showed a nondiagnostic image quality. All segments were included in the analysis. A total of 117 relevant lesions (diameter stenosis >50%) were detected using ICA, and 96 of 117 (82%) were detected by MDCT. Sensitivity, specificity, and positive and negative predictive values for the whole study group were as follows: 82%, 98%, 87%, and 97%, respectively. The correct clinical diagnosis of presence or absence of significant CAD was obtained in 65 of 72 (90%) patients. All stenoses were detected by MDCT in 52 of 72 (72%) patients. CONCLUSIONS: Our results indicate a high diagnostic accuracy of 16-slice MDCT with improved temporal resolution.
Authors: Georg Mühlenbruch; Marco Das; Christian Hohl; Joachim E Wildberger; Daniel Rinck; Thomas G Flohr; Ralf Koos; Christian Knackstedt; Rolf W Günther; Andreas H Mahnken Journal: Eur Radiol Date: 2005-12-22 Impact factor: 5.315
Authors: Andreas H Mahnken; Georg Mühlenbruch; Ralf Koos; Sven Stanzel; Petra Simone Busch; Mathias Niethammer; Rolf W Günther; Joachim E Wildberger Journal: Eur Radiol Date: 2006-04-11 Impact factor: 5.315
Authors: Marco A S Cordeiro; Albert C Lardo; Marcelo S V Brito; Miguel A Rosário Neto; Maria H A Siqueira; José R Parga; Luiz F Avila; José A F Ramires; João A C Lima; Carlos E Rochitte Journal: Int J Cardiovasc Imaging Date: 2006-03-15 Impact factor: 2.357
Authors: Anja J Reimann; Torsten Beck; Martin Heuschmid; Harald Brodoefel; Christof Burgstahler; Stephen Schröder; Andreas F Kopp Journal: Can J Cardiol Date: 2008-03 Impact factor: 5.223
Authors: A Romagnoli; E Martuscelli; M Sperandio; C Arganini; B De Angelis; V Acampora; A Patrei; G Bazzocchi; F Romeo; G Simonetti Journal: Radiol Med Date: 2009-12-16 Impact factor: 3.469