Literature DB >> 15626953

Haemophilus influenzae: a significant pathogen in acute otitis media.

Eugene Leibovitz1, Michael R Jacobs, Ron Dagan.   

Abstract

Haemophilus influenzae is a major pathogen in acute otitis media (AOM) causing disease that is not clinically distinguishable from that caused by Streptococcus pneumoniae. AOM caused by H. influenzae is particularly associated with older age and recurrent disease. Antibiotics differ in their ability to eradicate H. influenzae from the middle ear space. In the United States, widespread pneumococcal vaccination has increased the importance of H. influenzae as a major therapeutic challenge in the treatment of AOM.

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Year:  2004        PMID： 15626953

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  69 in total

1.  Antibodies specific for the high-molecular-weight adhesion proteins of nontypeable Haemophilus influenzae are opsonophagocytic for both homologous and heterologous strains.

Authors:  Linda E Winter; Stephen J Barenkamp
Journal:  Clin Vaccine Immunol       Date:  2006-10-04

2.  The inflammasome adaptor ASC contributes to multiple innate immune processes in the resolution of otitis media.

Authors:  Arwa Kurabi; Jasmine Lee; Chelsea Wong; Kwang Pak; Hal M Hoffman; Allen F Ryan; Stephen I Wasserman
Journal:  Innate Immun       Date:  2014-03-20       Impact factor: 2.680

3.  Interleukin-17A Aggravates Middle Ear Injury Induced by Streptococcus pneumoniae through the p38 Mitogen-Activated Protein Kinase Signaling Pathway.

Authors:  Wei Wang; Wenbin Liu; Jiali Liu; Zimeng Wang; Fangmei Fan; Yurong Ma; Chunfang Jin; Yun Xiang; Yifei Huang; Xuemei Zhang; Wenchun Xu; Yibing Yin; Yujuan He
Journal:  Infect Immun       Date:  2017-09-20       Impact factor: 3.441

4.  Cost-effectiveness evaluation of the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine for children in Taiwan.

Authors:  Chun-Yi Lu; Ching-Hu Chung; Li-Min Huang; Eliza Kruger; Seng-Chuen Tan; Xu-Hao Zhang; Nan-Chang Chiu
Journal:  Cost Eff Resour Alloc       Date:  2020-08-28

5.  Recognition of conserved antigens by Th17 cells provides broad protection against pulmonary Haemophilus influenzae infection.

Authors:  Wenchao Li; Xinyun Zhang; Ying Yang; Qingqin Yin; Yan Wang; Yong Li; Chuan Wang; Sandy M Wong; Ying Wang; Howard Goldfine; Brian J Akerley; Hao Shen
Journal:  Proc Natl Acad Sci U S A       Date:  2018-07-09       Impact factor: 11.205

Review 6.  Appropriate treatment of acute otitis media in the era of antibiotic resistance.

Authors:  Ron Dagan
Journal:  Paediatr Drugs       Date:  2010-06-29       Impact factor: 3.022

7.  Construction and immunogenicity of recombinant adenovirus vaccines expressing the HMW1, HMW2, or Hia adhesion protein of nontypeable Haemophilus influenzae.

Authors:  Linda E Winter; Stephen J Barenkamp
Journal:  Clin Vaccine Immunol       Date:  2010-08-04

8.  Impact of respiratory viral infections on α-hemolytic streptococci and otopathogens in the nasopharynx of young children.

Authors:  Victoria Friedel; Arthur Chang; Jennifer Wills; Roberto Vargas; Qingfu Xu; Michael E Pichichero
Journal:  Pediatr Infect Dis J       Date:  2013-01       Impact factor: 2.129

9.  Inflammation-associated cytokine analysis identifies presence of respiratory bacterial pathogens in the nasopharynx.

Authors:  Michael E Pichichero; Anthony Almudevar
Journal:  Pathog Dis       Date:  2016-08-04       Impact factor: 3.166

10.  The toll-Like receptor adaptor TRIF contributes to otitis media pathogenesis and recovery.

Authors:  Anke Leichtle; Michelle Hernandez; Kwang Pak; Nicholas J Webster; Stephen I Wasserman; Allen F Ryan
Journal:  BMC Immunol       Date:  2009-08-05       Impact factor: 3.615
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