Literature DB >> 1562619

Linear correlation between acetoacetate/beta-hydroxybutyrate in arterial blood and oxidized flavoprotein/reduced pyridine nucleotide in freeze-trapped human liver tissue.

K Ozawa1, B Chance, A Tanaka, S Iwata, T Kitai, I Ikai.   

Abstract

A comparison of two methods of measuring liver mitochondrial redox state demonstrated that a linear correlation exists between acetoacetate/beta-hydroxybutyrate ratio in arterial blood (arterial ketone body ratio; AKBR) and oxidized flavoprotein/reduced pyridine nucleotide in human liver tissue (FP/PN) as measured by tissue fluorescence spectroscopy, such that [FP/PN] = 0.64 + 0.49 x [AKBR] (r = 0.84, P less than 0.001). This result supports the validity of AKBR as a method of measuring the hepatic mitochondrial redox state of pyridine nucleotide using arterial blood.

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Year:  1992        PMID： 1562619     DOI： 10.1016/0925-4439(92)90014-e

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  19 in total

1.  The effects of intraoperative glucose infusion on portal blood insulin concentration and hepatic mitochondrial redox state during surgery: comparison of short-term and continuous infusions.

Authors:  J Hayakawa; H Motohashi; M Sairenji; O Kobayashi; M Takahashi; Y Usuda
Journal:  Surg Today       Date:  2000       Impact factor: 2.549

2.  Hepatic adenylate energy charge levels in patients with hepatoma after hepatic artery embolization.

Authors:  Li Li; Lu-Nan Yan; Xiao-Li Chen; Wu-Sheng Lu; Xiao-Dong Xie; Yan-Tao Wu
Journal:  World J Gastroenterol       Date:  1998-04       Impact factor: 5.742

3.  Optical Redox Imaging of Lonidamine Treatment Response of Melanoma Cells and Xenografts.

Authors:  He N Xu; Min Feng; Kavindra Nath; David Nelson; Jeff Roman; Huaqing Zhao; Zhenwu Lin; Jerry Glickson; Lin Z Li
Journal:  Mol Imaging Biol       Date:  2019-06       Impact factor: 3.488

4.  Optical redox imaging indices discriminate human breast cancer from normal tissues.

Authors:  He N Xu; Julia Tchou; Min Feng; Huaqing Zhao; Lin Z Li
Journal:  J Biomed Opt       Date:  2016-11-01       Impact factor: 3.170

5.  Functional deterioration of the liver by elevated inferior vena cava pressure: a proposed upper safety limit of pressure for maintaining liver viability in dogs.

Authors:  H Higashiyama; M Yamaguchi; K Kumada; H Sasaki; T Yamaguchi; K Ozawa
Journal:  Intensive Care Med       Date:  1994       Impact factor: 17.440

6.  Protective role of endogenous carbon monoxide in hepatic microcirculatory dysfunction after hemorrhagic shock in rats.

Authors:  B H Pannen; N Köhler; B Hole; M Bauer; M G Clemens; K K Geiger
Journal:  J Clin Invest       Date:  1998-09-15       Impact factor: 14.808

Review 7.  Imaging mitochondrial redox potential and its possible link to tumor metastatic potential.

Authors:  Lin Z Li
Journal:  J Bioenerg Biomembr       Date:  2012-12       Impact factor: 2.945

8.  IMAGING REDOX STATE HETEROGENEITY WITHIN INDIVIDUAL EMBRYONIC STEM CELL COLONIES.

Authors:  He N Xu; Russell C Addis; Davida F Goings; Shoko Nioka; Britton Chance; John D Gearhart; Lin Z Li
Journal:  J Innov Opt Health Sci       Date:  2011-07

Review 9.  Shedding light on mitochondrial function by real time monitoring of NADH fluorescence: II: human studies.

Authors:  Avraham Mayevsky; Efrat Barbiro-Michaely
Journal:  J Clin Monit Comput       Date:  2012-12-08       Impact factor: 2.502

10.  Significance of the hepatic mitochondrial redox state in the development of posttraumatic jaundice.

Authors:  T Nakatani; Y Endoh; K Kobayashi
Journal:  Surg Today       Date:  1995       Impact factor: 2.549
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