| Literature DB >> 15624970 |
Kerrie L Burgess1, Neil J Lajkiewicz, Amitav Sanyal, Wanlin Yan, John K Snyder.
Abstract
(-)-(R)-9-(1,2-Dimethoxyethyl)anthracene (8) is successfully employed as a chiral template in the Diels-Alder/retro-Diels-Alder sequence for the preparation of alpha,beta-unsaturated lactams. The cycloadditions proceed with complete diastereoselectivity, and regioselectivity in subsequent transformations of the carbonyl groups is also excellent. Flash vacuum pyrolysis accomplishes the cycloreversion.Entities:
Year: 2005 PMID： 15624970 DOI： 10.1021/ol047968a
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005