| Literature DB >> 15621450 |
Mario Juhas1, Lutz Wiehlmann, Prabhakar Salunkhe, Jörg Lauber, Jan Buer, Burkhard Tümmler.
Abstract
Two interlinked quorum sensing circuits, las and rhl, which control pathogenesis of Pseudomonas aeruginosa are further modulated by numerous regulators, including VqsR (virulence and quorum sensing regulator). High-density oligonucleotide microarrays were used to compare the global expression profile of a wild-type and VqsR mutant in ABC minimal medium. The expression of a large group of metabolic genes, ECF sigma factors as well as of many quorum-sensing genes previously not assigned to VqsR-regulon was found to be affected by the disruption of vqsR.Entities:
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Year: 2005 PMID： 15621450 DOI： 10.1016/j.femsle.2004.11.020
Source DB: PubMed Journal: FEMS Microbiol Lett ISSN： 0378-1097 Impact factor: 2.742