| Literature DB >> 15621289 |
Rajesh Gupta1, Jennifer L Beck, Margaret M Sheil, Stephen F Ralph.
Abstract
A combination of enzymatic digestion and electrospray ionisation mass spectrometry (ESI-MS) was used to characterise bifunctional adducts in which cisplatin is bound to GA base sequences in 8mer and 16mer oligonucleotides that do not contain other, higher affinity binding sites. The extent of formation of bifunctional adducts with GA base sequences was significant, but less than that seen with similar oligonucleotides containing either AG or GG sequences.Entities:
Mesh：
Substances：
Year: 2005 PMID： 15621289 DOI： 10.1016/j.jinorgbio.2004.11.001
Source DB: PubMed Journal: J Inorg Biochem ISSN： 0162-0134 Impact factor: 4.155