| Literature DB >> 15618529 |
Fotios Siannis1, John Copas, Guobing Lu.
Abstract
Most statistical methods for censored survival data assume there is no dependence between the lifetime and censoring mechanisms, an assumption which is often doubtful in practice. In this paper we study a parametric model which allows for dependence in terms of a parameter delta and a bias function B(t, theta). We propose a sensitivity analysis on the estimate of the parameter of interest for small values of delta. This parameter measures the dependence between the lifetime and the censoring mechanisms. Its size can be interpreted in terms of a correlation coefficient between the two mechanisms. A medical example suggests that even a small degree of dependence between the failure and censoring processes can have a noticeable effect on the analysis.Mesh:
Year: 2005 PMID: 15618529 DOI: 10.1093/biostatistics/kxh019
Source DB: PubMed Journal: Biostatistics ISSN: 1465-4644 Impact factor: 5.899