Min Hong1, Li Yu, Cheng Ma, Quan Zhu. 1. National Standard Lab of Pharmacology for Chinese Materia Medica, Nanjing 210029, Jiangsu, China. hongmin72@hotmail.com
Abstract
OBJECTIVE: To elucidate the difference between uterus body and cervix under the intervention of Shenghua decoction, and to observe the rabbit uterine muscle in the latest period of pregnancy for the way of myoelectric activity. METHOD: PowerLab/8s was used to record myoelectric activity of rabbit muscle in uterus body and cervix which was in a general anaesthesia state induced by urethane. RESULT: Myoelectric activities of rabbit uterine smooth muscle in the latest period of pregnancy was enhanced in vivo by being treated with Shenghua decoction 40 mg x kg(-1) (P < 0.01) while cervix myoelectric activities had no significant change (P < 0.05). CONCLUSION: Myoelectric activities of rabbit uterine muscle in the latest period of pregnancy are enhanced by being treated with Shenghua decoction so its hemostatic effect can be represented via the constriction of uterus body. Shenghua decoction is beneficial for child delivery because cervix myoelectric activities have no significant change under the intervention of Shenghua decoction while the myoelectric activities of uterus body are increased significantly.
OBJECTIVE: To elucidate the difference between uterus body and cervix under the intervention of Shenghua decoction, and to observe the rabbit uterine muscle in the latest period of pregnancy for the way of myoelectric activity. METHOD: PowerLab/8s was used to record myoelectric activity of rabbit muscle in uterus body and cervix which was in a general anaesthesia state induced by urethane. RESULT: Myoelectric activities of rabbit uterine smooth muscle in the latest period of pregnancy was enhanced in vivo by being treated with Shenghua decoction 40 mg x kg(-1) (P < 0.01) while cervix myoelectric activities had no significant change (P < 0.05). CONCLUSION: Myoelectric activities of rabbit uterine muscle in the latest period of pregnancy are enhanced by being treated with Shenghua decoction so its hemostatic effect can be represented via the constriction of uterus body. Shenghua decoction is beneficial for child delivery because cervix myoelectric activities have no significant change under the intervention of Shenghua decoction while the myoelectric activities of uterus body are increased significantly.
Authors: Mohd Rizal Abu Bakar; Azidah Abdul Kadir; Siti Zubaidah Abdul Wahab; Ahmad Helmy Abdul Karim; Nik Hazlina Nik Hussain; Norhayati Mohd Noor; Julia Omar; Saringat Bin Bai Bae; Wan Haslindawani Wan Mahmood; Asrenee Abdul Razak; Rohaizan Yunus Journal: PLoS One Date: 2015-07-29 Impact factor: 3.240