Literature DB >> 15616332

Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis in Brazil.

Vívian de F Sumnienski Rodrigues1, Maria Alice Telles, Marta Osório Ribeiro, Patrícia Izquierdo Cafrune, Maria Lucia Rosa Rossetti, Arnaldo Zaha.   

Abstract

In this study the nucleotide sequence of the pncA gene from 59 Mycobacterium tuberculosis clinical isolates was analyzed. Mutations in the pncA gene were identified in 29 of 40 pyrazinamide-resistant isolates, and no pyrazinamidase activity was detected in 39 of them. Twelve mutations found in this work have not been described previously.

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Year:  2005        PMID: 15616332      PMCID: PMC538919          DOI: 10.1128/AAC.49.1.444-446.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  32 in total

1.  pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates in Portugal.

Authors:  Isabel Portugal; Luís Barreiro; José Moniz-Pereira; Laura Brum
Journal:  Antimicrob Agents Chemother       Date:  2004-07       Impact factor: 5.191

2.  Pyrazinamide sterilizing activity in vitro against semidormant Mycobacterium tuberculosis bacterial populations.

Authors:  L Heifets; P Lindholm-Levy
Journal:  Am Rev Respir Dis       Date:  1992-05

3.  The action of antituberculosis drugs in short-course chemotherapy.

Authors:  D A Mitchison
Journal:  Tubercle       Date:  1985-09

4.  Supervised six-months treatment of newly diagnosed pulmonary tuberculosis using isoniazid, rifampin, and pyrazinamide with and without streptomycin.

Authors:  D E Snider; J Graczyk; E Bek; J Rogowski
Journal:  Am Rev Respir Dis       Date:  1984-12

5.  Simple pyrazinamidase and urease tests for routine identification of mycobacteria.

Authors:  L G Wayne
Journal:  Am Rev Respir Dis       Date:  1974-01

6.  Genetic and phenotypic characterization of pyrazinamide-resistant mycobacterium tuberculosis complex isolates in Japan.

Authors:  Chika Miyagi; Nobuhisa Yamane; Bhusal Yogesh; Hiromi Ano; Tetsuya Takashima
Journal:  Diagn Microbiol Infect Dis       Date:  2004-02       Impact factor: 2.803

7.  Accurate mapping of mutations of pyrazinamide-resistant Mycobacterium tuberculosis strains with a scanning-frame oligonucleotide microarray.

Authors:  Mary Margaret Wade; Dmitriy Volokhov; Mike Peredelchuk; Vladimir Chizhikov; Ying Zhang
Journal:  Diagn Microbiol Infect Dis       Date:  2004-06       Impact factor: 2.803

8.  Determination of pyrazinamide MICs for Mycobacterium tuberculosis at different pHs by the radiometric method.

Authors:  M Salfinger; L B Heifets
Journal:  Antimicrob Agents Chemother       Date:  1988-07       Impact factor: 5.191

9.  Use of pyrazinamidase activity on Mycobacterium tuberculosis as a rapid method for determination of pyrazinamide susceptibility.

Authors:  J K McClatchy; A Y Tsang; M S Cernich
Journal:  Antimicrob Agents Chemother       Date:  1981-10       Impact factor: 5.191

10.  Pyrazinamidase activity of Mycobacterium tuberculosis--a test of sensitivity to pyrazinamide.

Authors:  S S Trivedi; S G Desai
Journal:  Tubercle       Date:  1987-09
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  13 in total

1.  Role of pncA and rpsA gene sequencing in detection of pyrazinamide resistance in Mycobacterium tuberculosis isolates from southern China.

Authors:  Yaoju Tan; Zuqiong Hu; Tianyu Zhang; Xingshan Cai; Haobin Kuang; Yanwen Liu; Junyu Chen; Feng Yang; Ke Zhang; Shouyong Tan; Yanlin Zhao
Journal:  J Clin Microbiol       Date:  2013-10-16       Impact factor: 5.948

2.  Reevaluation of the critical concentration for drug susceptibility testing of Mycobacterium tuberculosis against pyrazinamide using wild-type MIC distributions and pncA gene sequencing.

Authors:  J Werngren; E Sturegård; P Juréen; K Ängeby; S Hoffner; T Schön
Journal:  Antimicrob Agents Chemother       Date:  2011-12-27       Impact factor: 5.191

3.  Systematic analysis of pyrazinamide-resistant spontaneous mutants and clinical isolates of Mycobacterium tuberculosis.

Authors:  Karolien Stoffels; Vanessa Mathys; Maryse Fauville-Dufaux; René Wintjens; Pablo Bifani
Journal:  Antimicrob Agents Chemother       Date:  2012-07-23       Impact factor: 5.191

Review 4.  Systematic review of mutations in pyrazinamidase associated with pyrazinamide resistance in Mycobacterium tuberculosis clinical isolates.

Authors:  Sarah M Ramirez-Busby; Faramarz Valafar
Journal:  Antimicrob Agents Chemother       Date:  2015-06-15       Impact factor: 5.191

5.  Peruvian and globally reported amino acid substitutions on the Mycobacterium tuberculosis pyrazinamidase suggest a conserved pattern of mutations associated to pyrazinamide resistance.

Authors:  Mirko Zimic; Patricia Sheen; Miguel Quiliano; Andrés Gutierrez; Robert H Gilman
Journal:  Infect Genet Evol       Date:  2009-12-04       Impact factor: 3.342

6.  Molecular epidemiological study of pyrazinamide-resistance in clinical isolates of mycobacterium tuberculosis from South India.

Authors:  Muthuraj Muthaiah; Sridharan Jagadeesan; Nisha Ayalusamy; Manupriya Sreenivasan; Sambamurthy Sangamesvara Prabhu; Usharani Muthuraj; Kamatchiyammal Senthilkumar; Saroja Veerappan
Journal:  Int J Mol Sci       Date:  2010-07-07       Impact factor: 5.923

7.  Pyrazinamide resistance and pncA gene mutations in Mycobacterium tuberculosis.

Authors:  Pontus Juréen; Jim Werngren; Juan-Carlos Toro; Sven Hoffner
Journal:  Antimicrob Agents Chemother       Date:  2008-03-03       Impact factor: 5.191

8.  Molecular dynamics simulations suggest ligand's binding to nicotinamidase/pyrazinamidase.

Authors:  Ji-Long Zhang; Qing-Chuan Zheng; Zheng-Qiang Li; Hong-Xing Zhang
Journal:  PLoS One       Date:  2012-06-26       Impact factor: 3.240

9.  Pyrazinamide Susceptibility and pncA Mutation Profiles of Mycobacterium tuberculosis among Multidrug-Resistant Tuberculosis Patients in Bangladesh.

Authors:  Arfatur Rahman; Sara Sabrina Ferdous; Shahriar Ahmed; S M Mazidur Rahman; Mohammad Khaja Mafij Uddin; Suporn Pholwat; Jean Gratz; Eric Houpt; Sayera Banu
Journal:  Antimicrob Agents Chemother       Date:  2017-08-24       Impact factor: 5.191

Review 10.  A Global Perspective on Pyrazinamide Resistance: Systematic Review and Meta-Analysis.

Authors:  Michael G Whitfield; Heidi M Soeters; Robin M Warren; Talita York; Samantha L Sampson; Elizabeth M Streicher; Paul D van Helden; Annelies van Rie
Journal:  PLoS One       Date:  2015-07-28       Impact factor: 3.240

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