| Literature DB >> 15616332 |
Vívian de F Sumnienski Rodrigues1, Maria Alice Telles, Marta Osório Ribeiro, Patrícia Izquierdo Cafrune, Maria Lucia Rosa Rossetti, Arnaldo Zaha.
Abstract
In this study the nucleotide sequence of the pncA gene from 59 Mycobacterium tuberculosis clinical isolates was analyzed. Mutations in the pncA gene were identified in 29 of 40 pyrazinamide-resistant isolates, and no pyrazinamidase activity was detected in 39 of them. Twelve mutations found in this work have not been described previously.Entities:
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Year: 2005 PMID: 15616332 PMCID: PMC538919 DOI: 10.1128/AAC.49.1.444-446.2005
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191