| Literature DB >> 15615514 |
Diane H Boschelli1, Biqi Wu, Ana Carolina Barrios Sosa, Haris Durutlic, Fei Ye, Yuri Raifeld, Jennifer M Golas, Frank Boschelli.
Abstract
We disclose here a new class of kinase inhibitors, obtained by replacing the phenyl ring of a 3-quinolinecarbonitrile system with a thiophene ring. When suitably substituted, the resultant 7-phenylaminothieno[3,2-b]pyridine-6-carbonitrile analogues show potent inhibition of Src kinase activity.Entities:
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Year: 2004 PMID： 15615514 DOI： 10.1021/jm049237m
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446