Literature DB >> 15604957

Increased sensitivity and confidence of SPECT over planar imaging in dual-phase sestamibi for parathyroid adenoma detection.

Andrew Slater1, Fergus V Gleeson.   

Abstract

UNLABELLED: PURPOSE OF REPORT: To determine the usefulness of SPECT imaging over planar imaging for the detection of parathyroid adenomas using dual-phase Tc-99m sestamibi.
MATERIALS AND METHODS: The records of patients referred for dual-phase sestamibi scintigraphy for detection of parathyroid adenomas were reviewed retrospectively. The images were reviewed blindly and planar images were compared with SPECT. The imaging results were compared with the operative results to determine the sensitivity, accuracy of localization, and confidence of the reporting radiologist.
RESULTS: The records of 37 patients were reviewed. Sensitivity was 62% for planar imaging and 73% for SPECT. There was one false positive. The side of the adenoma was correctly identified in all other patients. Confidence of detection was higher for SPECT than for planar imaging.
CONCLUSION: SPECT imaging increased the sensitivity and confidence of the detection of parathyroid adenomas. The results indicate that SPECT should be used for all preoperative parathyroid localization.

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Year:  2005        PMID: 15604957     DOI: 10.1097/00003072-200501000-00001

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN: 0363-9762            Impact factor:   7.794


  8 in total

Review 1.  SPECT/CT and tumour imaging.

Authors:  Gad Abikhzer; Zohar Keidar
Journal:  Eur J Nucl Med Mol Imaging       Date:  2013-08-29       Impact factor: 9.236

2.  Clinical impact of SPECT-CT in the diagnosis and surgical management of hyper-parathyroidism.

Authors:  Handan Tokmak; Mehmet Onur Demirkol; Faruk Alagöl; Serdar Tezelman; Tarik Terzioglu
Journal:  Int J Clin Exp Med       Date:  2014-04-15

3.  [Imaging diagnostics of hyperparathyroidism].

Authors:  S Delorme; C Zechmann; U Haberkorn
Journal:  Radiologe       Date:  2013-03       Impact factor: 0.635

Review 4.  Imaging techniques in parathyroid surgery for primary hyperparathyroidism.

Authors:  Arash Mohebati; Ashok R Shaha
Journal:  Am J Otolaryngol       Date:  2011-12-07       Impact factor: 1.808

5.  [18F]Fluorocholine Uptake of Parathyroid Adenoma Is Correlated with Parathyroid Hormone Level.

Authors:  Abdullah A Alharbi; Fahad M Alshehri; Abdulrahman A Albatly; Bert-Ram Sah; Christoph Schmid; Gerhard F Huber; Martin W Huellner
Journal:  Mol Imaging Biol       Date:  2018-10       Impact factor: 3.488

6.  Utility of intraoperative bilateral internal jugular venous sampling with rapid parathyroid hormone testing in guiding patients with a negative sestamibi scan for minimally invasive parathyroidectomy--a randomized controlled trial.

Authors:  Marcin Barczynski; Aleksander Konturek; Alicja Hubalewska-Dydejczyk; Stanislaw Cichon; Wojciech Nowak
Journal:  Langenbecks Arch Surg       Date:  2009-06-16       Impact factor: 3.445

7.  Comparison of five parathyroid scintigraphic protocols.

Authors:  Virpi Tunninen; Pekka Varjo; Jukka Schildt; Aapo Ahonen; Tomi Kauppinen; Irina Lisinen; Anu Holm; Hannu Eskola; Marko Seppänen
Journal:  Int J Mol Imaging       Date:  2013-01-21

8.  Incremental role of 18F-fluorocholine PET/CT over technetium-99m-labeled MIBI scan in hyperparathyroidism.

Authors:  Abhishek Behera; Nishikant Avinash Damle
Journal:  Indian J Endocrinol Metab       Date:  2016 Nov-Dec
  8 in total

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