Literature DB >> 15603937

Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives.

Jun Cheng1, Jiangtao Xie, Xianjin Luo.   

Abstract

Some benzimidazole derivatives were synthesized and evaluated for their antiviral properties. Compounds 20 and 21 showed potent selective activity against Coxsackie virus B(3) in VERO cells. Some structure-activity relationships were discussed.

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Year:  2005        PMID： 15603937     DOI： 10.1016/j.bmcl.2004.10.087

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  7 in total

1.  Assessment of the tautomeric population of benzimidazole derivatives in solution: a simple and versatile theoretical-experimental approach.

Authors:  Carlos Diaz; Ligia Llovera; Lorenzo Echevarria; Florencio E Hernández
Journal:  J Comput Aided Mol Des       Date:  2014-12-16       Impact factor: 3.686

Review 2.  Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review.

Authors:  Sumit Tahlan; Sanjiv Kumar; Balasubramanian Narasimhan
Journal:  BMC Chem       Date:  2019-08-06

Review 3.  Highlights in antiviral drug research: antivirals at the horizon.

Authors:  Erik De Clercq
Journal:  Med Res Rev       Date:  2012-05-02       Impact factor: 12.944

4.  By Modulating the Hormonal Balance and Ribonuclease Activity of Tomato Plants Bacillus subtilis Induces Defense Response against Potato Virus X and Potato Virus Y.

Authors:  Svetlana V Veselova; Antonina V Sorokan; Guzel F Burkhanova; Sergey D Rumyantsev; Ekaterina A Cherepanova; Valentin Y Alekseev; Elena R Sarvarova; Albina R Kasimova; Igor V Maksimov
Journal:  Biomolecules       Date:  2022-02-10

5.  1-benzyl-2-phenylbenzimidazole (BPB), a benzimidazole derivative, induces cell apoptosis in human chondrosarcoma through intrinsic and extrinsic pathways.

Authors:  Ju-Fang Liu; Yuan-Li Huang; Wei-Hung Yang; Chih-Shiang Chang; Chih-Hsin Tang
Journal:  Int J Mol Sci       Date:  2012-12-04       Impact factor: 5.923

6.  Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl2O4 as an effective catalyst.

Authors:  Javad Safari; Soheila Gandomi-Ravandi; Zahra Akbari
Journal:  J Adv Res       Date:  2012-12-21       Impact factor: 10.479

7.  4-(2-(1H-Benzo[d]imidazol-2-ylthio)acetamido)-N-(substituted phenyl)benzamides: design, synthesis and biological evaluation.

Authors:  Sumit Tahlan; Kalavathy Ramasamy; Siong Meng Lim; Syed Adnan Ali Shah; Vasudevan Mani; Balasubramanian Narasimhan
Journal:  BMC Chem       Date:  2019-02-02
  7 in total

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