Literature DB >> 15592799

Dietary-induced metabolic acidosis decreases bone mineral density in mature ovariectomized ewes.

J M MacLeay1, J D Olson, R M Enns, C M Les, C A Toth, D L Wheeler, A S Turner.   

Abstract

Dietary-induced metabolic acidosis (DIMA) may be a significant confounder in the development of osteoporosis. Diets that are acidifying are typically rich in proteins and grains and relatively poor in fruits and vegetables. Previous studies have not examined whether an interaction between estrogen depletion and DIMA have a compounded affect on bone mineral density loss. Sheep have been used successfully in previous studies to examine the interaction of bone turnover and ovariectomy. Therefore, the goal of this pilot study was to determine if bone mineral density (BMD) loss could be induced using DIMA in skeletally mature ovariectomized (OVX) ewes.

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Year:  2004        PMID： 15592799     DOI： 10.1007/s00223-004-0217-7

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN： 0171-967X            Impact factor:   4.333


  10 in total

1.  Osteopenia in the maxillofacial area: a study in sheep.

Authors:  E Veigel; R J Moore; M R Zarrinkalam; D Schulze; S Sauerbier; R Schmelzeisen; P J Voss
Journal:  Osteoporos Int       Date:  2010-05-26       Impact factor: 4.507

2.  Long-term effects of ovariectomy on the properties of bone in goats.

Authors:  Zhifeng Yu; Gang Wang; Tingting Tang; Lingjie Fu; Xiaowei Yu; Zhenan Zhu; Kerong Dai
Journal:  Exp Ther Med       Date:  2015-02-19       Impact factor: 2.447

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Authors:  Shiyong Wan; Wei Lei; Zixiang Wu; Da Liu; Mingxuan Gao; Suochao Fu
Journal:  Eur Spine J       Date:  2010-06-25       Impact factor: 3.134

Review 4.  Preclinical and Translational Studies in Small Ruminants (Sheep and Goat) as Models for Osteoporosis Research.

Authors:  Isabel R Dias; José A Camassa; João A Bordelo; Pedro S Babo; Carlos A Viegas; Nuno Dourado; Rui L Reis; Manuela E Gomes
Journal:  Curr Osteoporos Rep       Date:  2018-04       Impact factor: 5.096

5.  Fourier transform infrared imaging analysis of cancellous bone in alendronate- and raloxifene-treated osteopenic sheep.

Authors:  Ericka F Calton; Jennifer Macleay; Adele L Boskey
Journal:  Cells Tissues Organs       Date:  2011-05-19       Impact factor: 2.481

6.  Variations in nanomechanical properties and tissue composition within trabeculae from an ovine model of osteoporosis and treatment.

Authors:  Jayme C Burket; Daniel J Brooks; Jennifer M MacLeay; Shefford P Baker; Adele L Boskey; Marjolein C H van der Meulen
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Review 7.  Review of nonprimate, large animal models for osteoporosis research.

Authors:  Susan Reinwald; David Burr
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8.  Validation of the sheep as a large animal model for the study of vertebral osteoporosis.

Authors:  M R Zarrinkalam; H Beard; C G Schultz; R J Moore
Journal:  Eur Spine J       Date:  2008-11-18       Impact factor: 3.134

9.  The old sheep: a convenient and suitable model for senile osteopenia.

Authors:  Stefan Maenz; Olaf Brinkmann; Raimund W Kinne; Matthias Bungartz; Ines Hasenbein; Christina Braun; Elke Kunisch; Victoria Horbert; Francesca Gunnella; André Sachse; Sabine Bischoff; Harald Schubert; Klaus D Jandt; Jörg Bossert; Dominik Driesch
Journal:  J Bone Miner Metab       Date:  2020-04-15       Impact factor: 2.626

10.  The Effect of Osteoporosis Treatments on Fatigue Properties of Cortical Bone Tissue.

Authors:  Garry R Brock; Julia T Chen; Anthony R Ingraffea; Jennifer MacLeay; G Elizabeth Pluhar; Adele L Boskey; Marjolein C H van der Meulen
Journal:  Bone Rep       Date:  2015-06-01
  10 in total

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