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Literature DB >> 155909

Cyclosporin A: an immunosuppressive agent preferentially active against proliferating T cells.

D J White, A M Plumb, G Pawelec, G Brons.

Abstract

The in vitro action of the immunosuppressive agent Cyclospirin A has been investigated using porcine cells. Lymphocyte proliferation induced in response to transplantation antigens and phytohaemagglutinin (PHA), was inhibited by this agent at doses that failed to inhibit mitogenisis in response to sheep anti-pig IgM, growth of kidney cell monolayers, and leukocyte migration.

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Year: 1979 PMID： 155909

Source DB: PubMed Journal: Transplantation ISSN： 0041-1337 Impact factor: 4.939

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Cited

33 in total

1. Opsonic activity of cerebrospinal fluid in experimental cryptococcal meningitis.

Authors: M M Hobbs; J R Perfect; D L Granger; D T Durack
Journal: Infect Immun Date: 1990-07 Impact factor: 3.441

2. Prevention of diabetes mellitus in the BB/W rat with Cyclosporin-A.

Authors: A A Like; V Dirodi; S Thomas; D L Guberski; A A Rossini
Journal: Am J Pathol Date: 1984-10 Impact factor: 4.307

3. Herpes simplex virus infection and damage in the central nervous system: immunomodulation with adjuvant, cyclophosphamide and cyclosporin A.

Authors: S A Bishop; T J Hill
Journal: Arch Virol Date: 1991 Impact factor: 2.574

4. Hepatic and renal function in rats receiving immunotherapeutic doses of cyclosporin A.

Authors: P H Whiting; A W Thomson; I D Cameron; J G Simpson
Journal: Br J Exp Pathol Date: 1980-12

5. Suppression of delayed-type hypersensitivity reactions and lymphokine production by cyclosporin A in the mouse.

Authors: A W Thomson; D K Moon; D S Nelson
Journal: Clin Exp Immunol Date: 1983-06 Impact factor: 4.330

6. Selective induction of immunological tolerance in antiviral T killer cells of inbred mice after treatment with cyclosporin A.

Authors: D Armerding
Journal: Infect Immun Date: 1981-06 Impact factor: 3.441

7. Effect of cyclosporin A on in vitro proliferative activity and immunoglobulin synthesis of isolated human lymphoid cell subpopulations.

Authors: T Paavonen; H Järveläinen; S Kontiainen; P Häyry
Journal: Clin Exp Immunol Date: 1981-02 Impact factor: 4.330