Literature DB >> 15588253

Characterization of an archaeal family 4 uracil DNA glycosylase and its interaction with PCNA and chromatin proteins.

Isabelle Dionne1, Stephen D Bell.   

Abstract

We describe the characterization of a family 4 UDG1 (uracil DNA glycosylase) from the crenarchaeote Sulfolobus solfataricus. UDG1 is found to have a marked preference for substrates containing a G:U base pair over either A:U or single-stranded uracil-containing DNA substrates. UDG1 is found to interact with the sliding clamp PCNA (proliferating cell nuclear antigen), and does so by a conserved motif in the C-terminus of the protein. S. solfataricus has a heterotrimeric PCNA, and only one of the subunits, PCNA3, interacts with UDG1. We have been unable to detect any stimulation of UDG activity by PCNA, in contrast with the observed effects of PCNA on a number of DNA metabolic enzymes. However, analysis of the effects of Sulfolobus chromatin proteins on UDG1 leads us to propose a mechanistic basis for coupling UDG1 to the replication fork.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 15588253      PMCID： PMC1135018          DOI： 10.1042/BJ20041661

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  22 in total

1.  A read-ahead function in archaeal DNA polymerases detects promutagenic template-strand uracil.

Authors:  M A Greagg; M J Fogg; G Panayotou; S J Evans; B A Connolly; L H Pearl
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

2.  An archaeal XPF repair endonuclease dependent on a heterotrimeric PCNA.

Authors:  J A Roberts; S D Bell; M F White
Journal:  Mol Microbiol       Date:  2003-04       Impact factor: 3.501

Review 3.  The diverse spectrum of sliding clamp interacting proteins.

Authors:  Jonathan B Vivona; Zvi Kelman
Journal:  FEBS Lett       Date:  2003-07-10       Impact factor: 4.124

4.  Functional interactions of a homolog of proliferating cell nuclear antigen with DNA polymerases in Archaea.

Authors:  I K Cann; S Ishino; I Hayashi; K Komori; H Toh; K Morikawa; Y Ishino
Journal:  J Bacteriol       Date:  1999-11       Impact factor: 3.490

5.  Post-replicative base excision repair in replication foci.

Authors:  M Otterlei; E Warbrick; T A Nagelhus; T Haug; G Slupphaug; M Akbari; P A Aas; K Steinsbekk; O Bakke; H E Krokan
Journal:  EMBO J       Date:  1999-07-01       Impact factor: 11.598

6.  Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum.

Authors:  Sorel T Fitz-Gibbon; Heidi Ladner; Ung-Jin Kim; Karl O Stetter; Melvin I Simon; Jeffrey H Miller
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-15       Impact factor: 11.205

7.  Biochemical characterization of uracil processing activities in the hyperthermophilic archaeon Pyrobaculum aerophilum.

Authors:  A A Sartori; P Schär; S Fitz-Gibbon; J H Miller; J Jiricny
Journal:  J Biol Chem       Date:  2001-06-08       Impact factor: 5.157

8.  Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA.

Authors:  J M Gulbis; Z Kelman; J Hurwitz; M O'Donnell; J Kuriyan
Journal:  Cell       Date:  1996-10-18       Impact factor: 41.582

9.  The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation.

Authors:  Stephen D Bell; Catherine H Botting; Benjamin N Wardleworth; Stephen P Jackson; Malcolm F White
Journal:  Science       Date:  2002-04-05       Impact factor: 47.728

10.  Substrate requirements for duplex DNA translocation by the eukaryal and archaeal minichromosome maintenance helicases.

Authors:  Jae-Ho Shin; Yun Jiang; Beatrice Grabowski; Jerard Hurwitz; Zvi Kelman
Journal:  J Biol Chem       Date:  2003-09-15       Impact factor: 5.157
View more
  19 in total

1.  The hyperthermophilic euryarchaeon Archaeoglobus fulgidus repairs uracil by single-nucleotide replacement.

Authors:  Ingeborg Knævelsrud; Marivi N Moen; Kristin Grøsvik; Gyri T Haugland; Nils-Kåre Birkeland; Arne Klungland; Ingar Leiros; Svein Bjelland
Journal:  J Bacteriol       Date:  2010-05-07       Impact factor: 3.490

2.  Phylogenomic analysis of the uracil-DNA glycosylase superfamily.

Authors:  J Ignacio Lucas-Lledó; Rohan Maddamsetti; Michael Lynch
Journal:  Mol Biol Evol       Date:  2010-12-06       Impact factor: 16.240

3.  Roles of the Y-family DNA polymerase Dbh in accurate replication of the Sulfolobus genome at high temperature.

Authors:  Cynthia J Sakofsky; Patricia L Foster; Dennis W Grogan
Journal:  DNA Repair (Amst)       Date:  2012-02-04

4.  GINS, a central nexus in the archaeal DNA replication fork.

Authors:  Nina Marinsek; Elizabeth R Barry; Kira S Makarova; Isabelle Dionne; Eugene V Koonin; Stephen D Bell
Journal:  EMBO Rep       Date:  2006-02-17       Impact factor: 8.807

Review 5.  Uracil-DNA glycosylases-structural and functional perspectives on an essential family of DNA repair enzymes.

Authors:  N Schormann; R Ricciardi; D Chattopadhyay
Journal:  Protein Sci       Date:  2014-10-25       Impact factor: 6.725

6.  Biochemical evidence of a physical interaction between Sulfolobus solfataricus B-family and Y-family DNA polymerases.

Authors:  Mariarita De Felice; Barbara Medagli; Luca Esposito; Mariarosaria De Falco; Biagio Pucci; Mosè Rossi; Petr Grùz; Takehiko Nohmi; Francesca M Pisani
Journal:  Extremophiles       Date:  2006-11-03       Impact factor: 2.395

7.  Physical and functional interactions between uracil-DNA glycosylase and proliferating cell nuclear antigen from the euryarchaeon Pyrococcus furiosus.

Authors:  Shinichi Kiyonari; Maiko Uchimura; Tsuyoshi Shirai; Yoshizumi Ishino
Journal:  J Biol Chem       Date:  2008-06-18       Impact factor: 5.157

8.  Identification of a novel bifunctional uracil DNA glycosylase from Thermococcus barophilus Ch5.

Authors:  Likui Zhang; Donghao Jiang; Qi Gan; Haoqiang Shi; Li Miao; Yong Gong; Philippe Oger
Journal:  Appl Microbiol Biotechnol       Date:  2021-07-05       Impact factor: 4.813

9.  Assembly of viral metagenomes from yellowstone hot springs.

Authors:  Thomas Schoenfeld; Melodee Patterson; Paul M Richardson; K Eric Wommack; Mark Young; David Mead
Journal:  Appl Environ Microbiol       Date:  2008-04-25       Impact factor: 4.792

10.  Protein-protein interactions leading to recruitment of the host DNA sliding clamp by the hyperthermophilic Sulfolobus islandicus rod-shaped virus 2.

Authors:  Andrew F Gardner; Stephen D Bell; Malcolm F White; David Prangishvili; Mart Krupovic
Journal:  J Virol       Date:  2014-04-02       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.