Literature DB >> 15583703

Reelin glycoprotein: structure, biology and roles in health and disease.

S H Fatemi1.   

Abstract

Reelin glycoprotein is a secretory serine protease with dual roles in mammalian brain: embryologically, it guides neurons and radial glial cells to their corrected positions in the developing brain; in adult brain, Reelin is involved in a signaling pathway which underlies neurotransmission, memory formation and synaptic plasticity. Disruption of Reelin signaling pathway by mutations and selective hypermethylation of the Reln gene promoter or following various pre- or postnatal insults may lead to cognitive deficits present in neuropsychiatric disorders like autism or schizophrenia.

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Year:  2005        PMID： 15583703     DOI： 10.1038/sj.mp.4001613

Source DB:  PubMed          Journal:  Mol Psychiatry        ISSN： 1359-4184            Impact factor:   15.992


  69 in total

1.  Reelin, a marker of stress resilience in depression and psychosis.

Authors:  S Hossein Fatemi
Journal:  Neuropsychopharmacology       Date:  2011-11       Impact factor: 7.853

Review 2.  Emerging topics in Reelin function.

Authors:  Eckart Förster; Hans H Bock; Joachim Herz; Xuejun Chai; Michael Frotscher; Shanting Zhao
Journal:  Eur J Neurosci       Date:  2010-05       Impact factor: 3.386

3.  MEGF9: a novel transmembrane protein with a strong and developmentally regulated expression in the nervous system.

Authors:  Ulrike Brandt-Bohne; Douglas R Keene; Fletcher A White; Manuel Koch
Journal:  Biochem J       Date:  2007-01-15       Impact factor: 3.857

Review 4.  Schizophrenia and autism: both shared and disorder-specific pathogenesis via perinatal inflammation?

Authors:  Urs Meyer; Joram Feldon; Olaf Dammann
Journal:  Pediatr Res       Date:  2011-05       Impact factor: 3.756

Review 5.  A review of the fetal brain cytokine imbalance hypothesis of schizophrenia.

Authors:  Urs Meyer; Joram Feldon; Benjamin K Yee
Journal:  Schizophr Bull       Date:  2008-04-11       Impact factor: 9.306

6.  Reelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation.

Authors:  Jost Leemhuis; Elisabeth Bouché; Michael Frotscher; Frank Henle; Lutz Hein; Joachim Herz; Dieter K Meyer; Marina Pichler; Günter Roth; Carsten Schwan; Hans H Bock
Journal:  J Neurosci       Date:  2010-11-03       Impact factor: 6.167

7.  Epigenetic biomarkers in psychiatric disorders.

Authors:  J Peedicayil
Journal:  Br J Pharmacol       Date:  2008-06-23       Impact factor: 8.739

Review 8.  Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity.

Authors:  Barbara A Sorg; Sabina Berretta; Jordan M Blacktop; James W Fawcett; Hiroshi Kitagawa; Jessica C F Kwok; Marta Miquel
Journal:  J Neurosci       Date:  2016-11-09       Impact factor: 6.167

9.  Altered quality control in the endoplasmic reticulum causes cortical dysplasia in knock-in mice expressing a mutant BiP.

Authors:  Naoya Mimura; Shigeki Yuasa; Miho Soma; Hisayo Jin; Keita Kimura; Shigemasa Goto; Haruhiko Koseki; Tomohiko Aoe
Journal:  Mol Cell Biol       Date:  2007-10-22       Impact factor: 4.272

10.  Schizophrenia is associated with an increase in cortical microRNA biogenesis.

Authors:  N J Beveridge; E Gardiner; A P Carroll; P A Tooney; M J Cairns
Journal:  Mol Psychiatry       Date:  2009-09-01       Impact factor: 15.992
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