| Literature DB >> 15582449 |
Robert Pajewski1, Natasha Djedovic, Egan Harder, Riccardo Ferdani, Paul H Schlesinger, George W Gokel.
Abstract
A family of compounds having twin octadecyl anchor chains and various polar headgroups were designed to be ceramide mimics. The compounds prepared increase the apparent permeability of phospholipid vesicles to chloride and carboxyfluorescein anions. In addition, significantly larger vesicles are observed after exposure to these compounds suggesting the possibility of vesicular fusion.Entities:
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Year: 2005 PMID： 15582449 DOI： 10.1016/j.bmc.2004.10.001
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641