| Literature DB >> 15581578 |
Matthew W Vetting1, Luiz Pedro S de Carvalho, Michael Yu, Subray S Hegde, Sophie Magnet, Steven L Roderick, John S Blanchard.
Abstract
The Gcn5-related N-acetyltransferases are an enormous superfamily of enzymes that are universally distributed in nature and that use acyl-CoAs to acylate their cognate substrates. In this review, we will examine those members of this superfamily that have been both structurally and mechanistically characterized. These include aminoglycoside N-acetyltransferases, serotonin N-acetyltransferase, glucosamine-6-phosphate N-acetyltransferase, the histone acetyltransferases, mycothiol synthase, protein N-myristoyltransferase, and the Fem family of amino acyl transferases.Entities:
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Year: 2005 PMID： 15581578 DOI： 10.1016/j.abb.2004.09.003
Source DB: PubMed Journal: Arch Biochem Biophys ISSN： 0003-9861 Impact factor: 4.013