Literature DB >> 15579985

Resources involved in managing retinal detachment complicated by proliferative vitreoretinopathy.

Nandesh N Patel1, Catey Bunce, Riaz H Asaria, David G Charteris.   

Abstract

PURPOSE: To report the differences in cost of treatment and outcome in retinal detachment (RD) cases with and without proliferative vitreoretinopathy (PVR).
METHODS: Analysis of clinical trial databases of RD observed in 190 eyes of 190 patients. Eyes were classified as no PVR, developing PVR, or established PVR. For each eye, total cost of treatment undertaken on Moorfields Eye Hospital vitreoretinal unit, final retinal status, and best-corrected visual acuity were recorded.
RESULTS: Management of patients who developed PVR involved approximately double the resources of RD without PVR. Eyes with pre-exiting PVR had similar resource input to those with RD without PVR. Patients who developed PVR had a mean of 3.7 operations (including subsequent cataract surgery) compared to 1.8 and 2.1 respectively for noncomplicated RD and pre-existing PVR. Anatomic success and visual outcome was significantly worse in eyes with PVR.
CONCLUSIONS: Treatment of eyes that developed PVR after initial surgery cost significantly more than eyes with no PVR or established PVR (P < 0.01). Improvements in the management of RD aimed at preventing PVR and advances in PVR treatment may have significant financial as well as clinical benefits.

Entities:  

Mesh:

Year:  2004        PMID: 15579985     DOI: 10.1097/00006982-200412000-00007

Source DB:  PubMed          Journal:  Retina        ISSN: 0275-004X            Impact factor:   4.256


  15 in total

1.  Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy.

Authors:  Stephen G Schwartz; Harry W Flynn; Xue Wang; Ajay E Kuriyan; Samuel A Abariga; Wen-Hsiang Lee
Journal:  Cochrane Database Syst Rev       Date:  2020-05-13

2.  Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a nonangiogenic blinding disease.

Authors:  Steven Pennock; David Kim; Shizuo Mukai; Matthew Kuhnle; Dal W Chun; Joanne Matsubara; Jing Cui; Patrick Ma; David Maberley; Arif Samad; Robert J Van Geest; Sarit L Oberstein; Reinier O Schlingemann; Andrius Kazlauskas
Journal:  Am J Pathol       Date:  2013-04-09       Impact factor: 4.307

Review 3.  Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy.

Authors:  Stephen G Schwartz; Harry W Flynn; Wen-Hsiang Lee; Elizabeth Ssemanda; Ann-Margret Ervin
Journal:  Cochrane Database Syst Rev       Date:  2009-10-07

Review 4.  Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy.

Authors:  Stephen G Schwartz; Harry W Flynn; Wen-Hsiang Lee; Xue Wang
Journal:  Cochrane Database Syst Rev       Date:  2014-02-14

Review 5.  [Proliferative vitreoretinopathy process-To heal or not to heal].

Authors:  S Grisanti; S Priglinger; L Hattenbach
Journal:  Ophthalmologe       Date:  2021-01       Impact factor: 1.059

Review 6.  Steroids as an adjunct for reducing the incidence of proliferative vitreoretinopathy after rhegmatogenous retinal detachment surgery: a systematic review and meta-analysis.

Authors:  Hui Shi; Tao Guo; Peng-Cheng Liu; Qian-Yi Wang; Ya-Ru Du; Qing-Yu Liu; Meng-Mei He; Jun-Ling Liu; Jing Yu
Journal:  Drug Des Devel Ther       Date:  2015-03-06       Impact factor: 4.162

Review 7.  Mechanisms of inflammation in proliferative vitreoretinopathy: from bench to bedside.

Authors:  Stavros N Moysidis; Aristomenis Thanos; Demetrios G Vavvas
Journal:  Mediators Inflamm       Date:  2012-09-25       Impact factor: 4.711

8.  Rhegmatogenous retinal detachment in Scotland: research design and methodology.

Authors:  Danny Mitry; David G Charteris; David Yorston; Brian W Fleck; Alan Wright; Harry Campbell; Jaswinder Singh
Journal:  BMC Ophthalmol       Date:  2009-03-24       Impact factor: 2.209

9.  Ozurdex (a slow-release dexamethasone implant) in proliferative vitreoretinopathy: study protocol for a randomised controlled trial.

Authors:  Philip J Banerjee; Catey Bunce; David G Charteris
Journal:  Trials       Date:  2013-10-28       Impact factor: 2.279

10.  The T309G MDM2 gene polymorphism is a novel risk factor for proliferative vitreoretinopathy.

Authors:  Salvador Pastor-Idoate; Irene Rodríguez-Hernández; Jimena Rojas; Itziar Fernández; María T García-Gutiérrez; José M Ruiz-Moreno; Amandio Rocha-Sousa; Yashin Ramkissoon; Steven Harsum; Robert E MacLaren; David Charteris; Jan C VanMeurs; Rogelio González-Sarmiento; José C Pastor
Journal:  PLoS One       Date:  2013-12-09       Impact factor: 3.240

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